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Opsin 3 (OPN3) (AA 300-400) antibody

Details for Product No. ABIN350681
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Antigen
Synonyms ERO, Ecpn, panopsin, ECPN, OPN3
Epitope
AA 300-400
(15), (9), (2), (1), (1), (1), (1), (1)
Reactivity
Human, Rat (Rattus), Mouse (Murine)
(44), (22), (1)
Host
Sheep
(47)
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(36), (27), (12), (10), (10), (4), (1), (1)
Pubmed 3 references available
Quantity 100 µL
Options
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Availability Will be delivered in 7 to 8 Business Days
Catalog No. ABIN350681
454.67 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen A synthetic peptide from AA 300-400 of mouse encephalopsin conjugated to an immunogenic carrier protein was used as the antigen.
Isotype IgG
Specificity Specific for RhOA.
Purification whole serum
Alternative Name Opsin-3 (OPN3, ECPN, encephalopsin, panopsin)
Background Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. In addition to the visual opsins, mammals possess several photoreceptive non-visual opsins that are expressed in extraocular tissues. This gene, opsin 3, is strongly expressed in brain and testis and weakly expressed in liver, placenta, heart, lung, skeletal muscle, kidney, and pancreas. The gene may also be expressed in the retina. The protein has the canonical features of a photoreceptive opsin protein.
Function: May play a role in encephalic photoreception.
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Strongly expressed in brain. Highly expressed in the preoptic area and paraventricular nucleus of the hypothalamus. Shows highly patterned expression in other regions of the brain, being enriched in selected regions of the cerebral cortex, cerebellar Purkinje cells, a subset of striatal neurons, selected thalamic nuclei, and a subset of interneurons in the ventral horn of the spinal cord. Also known as: Opsin-3, encephalopsin, panopsin, OPN3, ECPN, opsin 3.
UniProt Q9QUI0
Research Area Cancer, Cytoskeleton, Microfilaments
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Liquid
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term.
Expiry Date 12 months
General Blackshaw, Snyder: "Encephalopsin: a novel mammalian extraretinal opsin discretely localized in the brain." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 19, Issue 10, pp. 3681-90, 1999 (PubMed).

Kasper, Taudien, Staub et al.: "Different structural organization of the encephalopsin gene in man and mouse." in: Gene, Vol. 295, Issue 1, pp. 27-32, 2002 (PubMed).

Carninci, Kasukawa, Katayama et al.: "The transcriptional landscape of the mammalian genome...." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1559-63, 2005 (PubMed).

Hosts (47)
Reactivities (44), (22), (1)
Applications (36), (27), (12), (10), (10), (4), (1), (1)
Epitopes (15), (9), (2), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN350681
454.67 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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