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Details for Product No. ABIN350681

Opsin 3 (OPN3) antibody

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Antigen
Synonyms ERO, Ecpn, panopsin, ECPN, OPN3
Reactivity
»Alternatives Mouse (Murine)
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN350681
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from mouse opsin-3 (OPN3, ECPN, encephalopsin, panopsin) conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Appears to be specific for opsin-3.
Purity whole serum
Alternative Name Opsin-3 (OPN3, ECPN, encephalopsin, panopsin)
Background Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. In addition to the visual opsins, mammals possess several photoreceptive non-visual opsins that are expressed in extraocular tissues. This gene, opsin 3, is strongly expressed in brain and testis and weakly expressed in liver, placenta, heart, lung, skeletal muscle, kidney, and pancreas. The gene may also be expressed in the retina. The protein has the canonical features of a photoreceptive opsin protein.
Function: May play a role in encephalic photoreception.
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Strongly expressed in brain. Highly expressed in the preoptic area and paraventricular nucleus of the hypothalamus. Shows highly patterned expression in other regions of the brain, being enriched in selected regions of the cerebral cortex, cerebellar Purkinje cells, a subset of striatal neurons, selected thalamic nuclei, and a subset of interneurons in the ventral horn of the spinal cord. Also known as: Opsin-3, encephalopsin, panopsin, OPN3, ECPN, opsin 3.
UniProt Q9WUK7
Application Notes IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Blackshaw, Snyder: "Encephalopsin: a novel mammalian extraretinal opsin discretely localized in the brain." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 19, Issue 10, pp. 3681-90, 1999 (PubMed).

Kasper, Taudien, Staub et al.: "Different structural organization of the encephalopsin gene in man and mouse." in: Gene, Vol. 295, Issue 1, pp. 27-32, 2002 (PubMed).

Carninci, Kasukawa, Katayama et al.: "The transcriptional landscape of the mammalian genome." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1559-63, 2005 (PubMed).

Alternatives for antigen "Opsin 3 (OPN3)", type "Antibodies"
Hosts (43)
Reactivities (42), (19), (1)
Applications (32), (23), (13), (9), (9), (3), (1), (1)
Epitopes (15), (8), (1), (1), (1)
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