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Details for Product No. ABIN350686

ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2) (C-Term) antibody

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Antigen
Synonyms C7orf19, CBCIP2, MEM142B, TMEM142B, Tmem142b, A730041O15Rik, RGD1310213, ORAI2, Orai2, LOC100230993, tmem142b
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Mouse (Murine), Rat (Rattus), Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN350686
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from the c-terminal region of mouse Orai2 (TMEM142b) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in rat and human.
Specificity Appears to be specific for Orai2.
Purity whole serum
Alternative Name Orai2 (TMEM142b)
Background Function: Ca2+ release-activated Ca2+-like (CRAC-like) channel subunit which mediates Ca2+ influx and increase in Ca2+-selective current by synergy with the Ca2+ sensor, STIM1.
Subcellular location: Cell membrane, Multi-pass membrane protein. Also known as: Protein orai-2,transmembrane protein 142B, CAP-binding protein complex-interacting protein 2, C7orf19, CBCIP2, TMEM142B.
UniProt Q8BH10
Application Notes IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Hillier, Fulton, Fulton et al.: "The DNA sequence of human chromosome 7." in: Nature, Vol. 424, Issue 6945, pp. 157-64, 2003 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Carninci, Kasukawa, Katayama et al.: "The transcriptional landscape of the mammalian genome." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1559-63, 2005 (PubMed).

Feske, Gwack, Prakriya et al.: "A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function." in: Nature, Vol. 441, Issue 7090, pp. 179-85, 2006 (PubMed).

Mercer, Dehaven, Smyth et al.: "Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1." in: The Journal of biological chemistry, Vol. 281, Issue 34, pp. 24979-90, 2006 (PubMed).

Alternatives for antigen "ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2)", type "Antibodies"
Hosts (33)
Reactivities (31), (23), (13), (13), (12), (12)
Applications (24), (11), (10), (9), (9), (3), (2), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (12), (1), (1)
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