P2X5 (P2RX5, P2X purinoceptor 5, ATP receptor) (Cytoplasmic Domain) antibody

Antigen: P2X5 (P2RX5, P2X purinoceptor 5, ATP receptor)

Binding Site: Cytoplasmic Domain

Clonality: Polyclonal

Host: Rabbit

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350699

Additional Information

UniProt: Q93086

Immunogen: A synthetic peptide from the cytoplasmic domain of human P2X5 (P2RX5, P2X purinoceptor 5, ATP receptor) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: Function: Receptor for ATP that acts as a ligand gated ion channel. Subcellular location: Membrane; Multi-pass membrane protein. Tissue specificity: Expressed at high levels in brain and immune system. Also known as: P2X5, P2RX5, P2X purinoceptor 5, ATP receptor, Purinergic receptor.

Specificity: Appears to be specific for P2RX5.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Purity: whole serum

Purification: Purified mouse LPS-activated B cells

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Lue, Paquet, Nouel et al.: "Primary structure and expression of a naturally truncated human P2X ATP receptor subunit from brain and immune system." in: FEBS letters, Vol. 418, Issue 1-2, pp. 195-9, 1998 (PubMed).

Touchman, Anikster, Dietrich et al.: "The genomic region encompassing the nephropathic cystinosis gene (CTNS): complete sequencing of a 200-kb segment and discovery of a novel gene within the common cystinosis-causing deletion." in: Genome research, Vol. 10, Issue 2, pp. 165-73, 2000 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Yu, Zhu, Chan et al.: "Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra." in: Journal of proteome research, Vol. 6, Issue 11, pp. 4150-62, 2007 (PubMed).