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P2X5 (P2RX5, P2X purinoceptor 5, ATP receptor) (Cytoplasmic Domain) antibody
Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
|4 references available|
|Quantity||100 µl (Variants)|
|Price||454.67 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 7 to 8 Business Days|
|Immunogen||A synthetic peptide from the cytoplasmic domain of rat P2X5 (P2RX5, P2X purinoceptor 5, ATP receptor) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen shares 90% identity with mouse sequence.|
|Description||Function: Receptor for ATP that acts as a ligand gated ion channel. Subcellular location: Membrane; Multi-pass membrane protein. Tissue specificity: Expressed at high levels in brain and immune system. Also known as: P2X5, P2RX5, P2X purinoceptor 5, ATP receptor, Purinergic receptor.|
|Specificity||Appears to be specific for P2RX5.|
|Application Notes||IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.|
|Purification||Purified mouse LPS-activated B cells|
|Storage||Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.|
|Restrictions||For Research Use only|
Lue, Paquet, Nouel et al.: "Primary structure and expression of a naturally truncated human P2X ATP receptor subunit from brain and immune system." in: FEBS letters, Vol. 418, Issue 1-2, pp. 195-9, 1998 (PubMed).
Touchman, Anikster, Dietrich et al.: "The genomic region encompassing the nephropathic cystinosis gene (CTNS): complete sequencing of a 200-kb segment and discovery of a novel gene within the common cystinosis-causing deletion." in: Genome research, Vol. 10, Issue 2, pp. 165-73, 2000 (PubMed).
Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).
Yu, Zhu, Chan et al.: "Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra." in: Journal of proteome research, Vol. 6, Issue 11, pp. 4150-62, 2007 (PubMed).
|Applications||Immunohistochemistry (IHC) (1), Western Blotting (WB) (1)|
|Epitopes||Cytoplasmic Domain (1)|