Purinergic Receptor P2X, Lig-Nd-Gated Ion Channel, 6 (P2RX6) (extracellular domain) antibody

Antigen: Purinergic Receptor P2X, Lig-Nd-Gated Ion Channel, 6 (P2RX6)

Synonyms: P2X6, P2XM, P2RXL1, MGC129625

Epitope: extracellular domain

Clonality: Polyclonal

Host: Rabbit

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350701

Additional Information

Alternative name: P2X6 (P2RX6, P2X purinoceptor 6, ATP receptor, P2RXL1) (extracellular domain)

Swiss-Prot: O15547

Immunogen: A synthetic peptide from the extracellular domain of human P2X6 (P2RX6, P2X purinoceptor 6, ATP receptor, P2RXL1) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen shares 90% identity with mouse sequence.

Format: Lyophilized

Description: Function: Receptor for ATP that acts as a ligand gated ion channel Subcellular location: Membrane; Multi-pass membrane protein. Tissue specificity: Expressed predominantly in skeletal muscle. Also known as: P2RX6, P2X purinoceptor 6, ATP receptor, Purinergic receptor, P2RXL1.

Specificity: Appears to be specific for P2RX6.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Publications: Urano, Nishimori, Han et al.: "Cloning of P2XM, a novel human P2X receptor gene regulated by p53." in: Cancer research, Vol. 57, Issue 15, pp. 3281-7, 1997 (PubMed).

Maguire, Wynne, Harney et al.: "Identification of the phosphotyrosine proteome from thrombin activated platelets." in: Proteomics, Vol. 2, Issue 6, pp. 642-8, 2002 (PubMed).

Collins, Wright, Edwards et al.: "A genome annotation-driven approach to cloning the human ORFeome." in: Genome biology, Vol. 5, Issue 10, pp. R84, 2004 (PubMed).