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Purinergic Receptor P2X, Ligand-Gated Ion Channel, 6 (P2RX6) (AA 350-400) antibody

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Antigen
  • P2RXL1
  • P2RX6
  • P2X6
  • P2XM
  • P2rxl1
  • P2x6
  • P2xm
  • Rnap2x6
Epitope
AA 350-400
15
13
13
11
6
4
2
2
2
2
1
1
1
Reactivity
Human
60
32
32
1
1
1
Host
Rabbit
65
1
Clonality
Polyclonal
Conjugate
Un-conjugated
4
4
4
3
2
2
2
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (IHC), Western Blotting (WB)
43
22
16
7
3
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Immunogen A synthetic peptide from aa region 350-400 of human P2X6 conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 90% identity with mouse sequence.
Specificity Specific for P2RX6.
Purification Whole serum
Alternative Name P2RX6 (P2RX6 Antibody Abstract)
Background Function: Receptor for ATP that acts as a ligand gated ion channel
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Expressed predominantly in skeletal muscle. Also known as: P2RX6, P2X purinoceptor 6, ATP receptor, Purinergic receptor, P2RXL1.
Pathways
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Collins, Wright, Edwards et al.: "A genome annotation-driven approach to cloning the human ORFeome." in: Genome biology, Vol. 5, Issue 10, pp. R84, 2004 (PubMed).

Maguire, Wynne, Harney et al.: "Identification of the phosphotyrosine proteome from thrombin activated platelets." in: Proteomics, Vol. 2, Issue 6, pp. 642-8, 2002 (PubMed).

Urano, Nishimori, Han et al.: "Cloning of P2XM, a novel human P2X receptor gene regulated by p53." in: Cancer research, Vol. 57, Issue 15, pp. 3281-7, 1997 (PubMed).