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Details for Product No. ABIN350703

Purinergic Receptor P2X, Ligand-Gated Ion Channel, 6 (P2RX6) (Cytoplasmic Domain) antibody

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Antigen
Synonyms P2rxl1, P2x6, P2xm, P2RXL1, Rnap2x6, P2X6, P2XM, P2RX6
Epitope
»Alternatives Cytoplasmic Domain
Reactivity
»Alternatives Mouse (Murine), Rat (Rattus), Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 4 references available
Catalog no. ABIN350703
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from the cytoplasmic domain of mouse P2X6 (P2RX6, P2X purinoceptor 6, ATP receptor, P2RXL1) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in rat and shares 86% identity with human sequence.
Specificity Appears to be specific for P2RX6.
Purification Purified mouse LPS-activated B cells
Purity whole serum
Alternative Name P2X6 (P2RX6, P2X purinoceptor 6, ATP receptor, P2RXL1, P2XM)
Background Function: Receptor for ATP that acts as a ligand gated ion channel
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Expressed predominantly in skeletal muscle. Also known as: P2RX6, P2X purinoceptor 6, ATP receptor, Purinergic receptor, P2RXL1, P2XM.
UniProt O54803
Application Notes IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Urano, Nishimori, Han et al.: "Cloning of P2XM, a novel human P2X receptor gene regulated by p53." in: Cancer research, Vol. 57, Issue 15, pp. 3281-7, 1997 (PubMed).

Nawa, Urano, Tokino et al.: "Cloning and characterization of the murine P2XM receptor gene." in: Journal of human genetics, Vol. 43, Issue 4, pp. 262-7, 1999 (PubMed).

Maguire, Wynne, Harney et al.: "Identification of the phosphotyrosine proteome from thrombin activated platelets." in: Proteomics, Vol. 2, Issue 6, pp. 642-8, 2002 (PubMed).

Collins, Wright, Edwards et al.: "A genome annotation-driven approach to cloning the human ORFeome." in: Genome biology, Vol. 5, Issue 10, pp. R84, 2004 (PubMed).

Alternatives for antigen "Purinergic Receptor P2X, Ligand-Gated Ion Channel, 6 (P2RX6)", type "Antibodies"
Hosts (33)
Reactivities (29), (22), (20), (18), (17), (1), (1)
Applications (19), (15), (10), (6), (4), (3), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (4), (3), (2), (2), (1), (1), (1), (1)
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