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Details for Product No. ABIN350704

Purinergic Receptor P2X, Ligand-Gated Ion Channel, 6 (P2RX6) antibody

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Antigen
Synonyms P2rxl1, P2x6, P2xm, P2RXL1, Rnap2x6, P2X6, P2XM, P2RX6
Reactivity
»Alternatives Mouse (Murine)
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 4 references available
Catalog no. ABIN350704
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from AA of 355-375 of mouse P2X6 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat and shares 86% identity with human sequence.
Specificity Specific for VN1B8.
Purification Purified mouse LPS-activated B cells
Purity IgG
Alternative Name P2X6 (P2RX6, P2X purinoceptor 6, ATP receptor, P2RXL1, P2XM)
Background Function: Receptor for ATP that acts as a ligand gated ion channel
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Expressed predominantly in skeletal muscle. Also known as: P2RX6, P2X purinoceptor 6, ATP receptor, Purinergic receptor, P2RXL1, P2XM.
UniProt Q9EQ45
Application Notes A concentration of 10-50 µg/mL is recommended.
The optimal concentration should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
Expiry Date 12 months
Urano, Nishimori, Han et al.: "Cloning of P2XM, a novel human P2X receptor gene regulated by p53." in: Cancer research, Vol. 57, Issue 15, pp. 3281-7, 1997 (PubMed).

Nawa, Urano, Tokino et al.: "Cloning and characterization of the murine P2XM receptor gene." in: Journal of human genetics, Vol. 43, Issue 4, pp. 262-7, 1999 (PubMed).

Maguire, Wynne, Harney et al.: "Identification of the phosphotyrosine proteome from thrombin activated platelets." in: Proteomics, Vol. 2, Issue 6, pp. 642-8, 2002 (PubMed).

Collins, Wright, Edwards et al.: "A genome annotation-driven approach to cloning the human ORFeome." in: Genome biology, Vol. 5, Issue 10, pp. R84, 2004 (PubMed).

Alternatives for antigen "Purinergic Receptor P2X, Ligand-Gated Ion Channel, 6 (P2RX6)", type "Antibodies"
Hosts (32), (1)
Reactivities (26), (21), (20), (18), (17), (1), (1)
Applications (19), (15), (10), (6), (4), (3), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (4), (3), (3), (2), (1), (1), (1), (1), (1)
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