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NGFR antibody

NGFR Reactivity: Human WB, FACS, IHC, Purif Host: Mouse Monoclonal unconjugated
Catalog No. ABIN350715
  • Target See all NGFR Antibodies
    NGFR (Nerve Growth Factor Receptor (NGFR))
    Reactivity
    • 160
    • 61
    • 55
    • 29
    • 27
    • 26
    • 26
    • 21
    • 11
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 92
    • 75
    • 4
    • 1
    Mouse
    Clonality
    • 92
    • 80
    Monoclonal
    Conjugate
    • 90
    • 15
    • 12
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NGFR antibody is un-conjugated
    Application
    • 105
    • 81
    • 61
    • 55
    • 48
    • 30
    • 27
    • 20
    • 20
    • 14
    • 14
    • 12
    • 9
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Purification (Purif)
    Specificity
    Specific for p75NTR.
    Cross-Reactivity
    Cat, Dog, Human, Marmoset, Pig, Rabbit
    Purification
    Affinity purified
    Immunogen
    Human melanoma cell lines
    Isotype
    IgG1, IgG1 kappa
    Top Product
    Discover our top product NGFR Primary Antibody
  • Application Notes
    IHC, WB, FC. A concentration of 2-10 μg,ml is recommended. The optimal working concentration should be determined by the end user. This antibody may also be used for immunoabsorptive purification of NGF-receptors. See also the eLab Book at the end of this page.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.
    Handling Advice
    Avoid freeze and thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Expiry Date
    12 months
  • Target
    NGFR (Nerve Growth Factor Receptor (NGFR))
    Alternative Name
    p75NTR (NGFR Products)
    Background
    FUNCTION: Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. SUBUNIT: Homodimer, disulfide-linked. Interacts with p75NTR-associated cell death executor. Interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1 and NGFRAP1/BEX3. SUBCELLULAR LOCATION: Membrane, Single-pass type I membrane protein.,Olfactory Related,Tumor necrosis factor receptor superfamily member 16, P08138, low-affinity nerve growth factor receptor, NGF receptor, Gp80-LNGFR, p75 ICD, low affinity neurotrophin receptor p75NTR, CD271 antigen, NGFR, TNFRSF16
    UniProt
    P08138
    Pathways
    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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