Add to Basket
|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Paraneoplastic Antigen MA2 (PNMA2) (C-Term) antibody
|Synonyms||MA2, MM2, RGAG2, KIAA0883, PNMA2, mKIAA0883, A830049P17Rik, MGC137318, DKFZp459C042|
Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
|4 references available|
|Price||454.67 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 7 to 8 Business Days|
|Alternative name||Paraneoplastic antigen Ma2|
|Immunogen||A synthetic peptide from c-terminal region of human Paraneoplastic antigen Ma2 conjugated to an immunogenic carrier protein was used as the immunogen.|
|Description||SUBCELLULAR LOCATION: Nucleus › nucleolus. Tissue specificity: Brain specific. In some patients suffering from cancers, it is also specifically expressed by the testicular tumor cells. Also known as: Onconeuronal antigen Ma2, Paraneoplastic neuronal antigen MM2, 40 kDa neuronal protein, PNMA2, MA2.|
|Specificity||Appears to be specific for PNMA2.|
|Application Notes||IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications.|
|Storage||Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.|
|Restrictions||For Research Use only|
Nagase, Ishikawa, Suyama et al.: "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 5, Issue 6, pp. 355-64, 1999 (PubMed).
Dalmau, Gultekin, Voltz et al.: "Ma1, a novel neuron- and testis-specific protein, is recognized by the serum of patients with paraneoplastic neurological disorders." in: Brain : a journal of neurology, Vol. 122 ( Pt 1), pp. 27-39, 1999 (PubMed).
Voltz, Gultekin, Rosenfeld et al.: "A serologic marker of paraneoplastic limbic and brain-stem encephalitis in patients with testicular cancer." in: The New England journal of medicine, Vol. 340, Issue 23, pp. 1788-95, 1999 (PubMed).
Rosenfeld, Eichen, Wade et al.: "Molecular and clinical diversity in paraneoplastic immunity to Ma proteins." in: Annals of neurology, Vol. 50, Issue 3, pp. 339-48, 2001 (PubMed).