Paraneoplastic Antigen MA2 (PNMA2) (C-Term) antibody

Details for Product No. ABIN350724
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Antigen
Synonyms PNMA2, DKFZp459C042, A830049P17Rik, mKIAA0883, MA2, MM2, RGAG2
Epitope
C-Term
(3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(25), (4), (3)
Host
Rabbit
(21), (5)
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(22), (15), (3), (3), (2), (2), (1)
Pubmed 4 references available
Quantity 100 µL
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Catalog No. ABIN350724
454.67 $
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Immunogen A synthetic peptide from c-terminal region of human Paraneoplastic antigen Ma2 conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Specific for PNMA2.
Purification Whole serum
Alternative Name MA2
Background SUBCELLULAR LOCATION: Nucleus › nucleolus.
Tissue specificity: Brain specific. In some patients suffering from cancers, it is also specifically expressed by the testicular tumor cells. Also known as: Onconeuronal antigen Ma2, Paraneoplastic neuronal antigen MM2, 40 kDa neuronal protein, PNMA2, MA2.
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user. Not tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
General Nagase, Ishikawa, Suyama et al.: "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 5, Issue 6, pp. 355-64, 1999 (PubMed).

Dalmau, Gultekin, Voltz et al.: "Ma1, a novel neuron- and testis-specific protein, is recognized by the serum of patients with paraneoplastic neurological disorders." in: Brain : a journal of neurology, Vol. 122 ( Pt 1), pp. 27-39, 1999 (PubMed).

Voltz, Gultekin, Rosenfeld et al.: "A serologic marker of paraneoplastic limbic and brain-stem encephalitis in patients with testicular cancer." in: The New England journal of medicine, Vol. 340, Issue 23, pp. 1788-95, 1999 (PubMed).

Rosenfeld, Eichen, Wade et al.: "Molecular and clinical diversity in paraneoplastic immunity to Ma proteins." in: Annals of neurology, Vol. 50, Issue 3, pp. 339-48, 2001 (PubMed).

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