BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (C-Term) antibody

Details for Product No. ABIN350733
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Antigen
Synonyms NIP3, Nip3
Epitope
C-Term
(12), (10), (6), (5), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Rat (Rattus), Mouse (Murine), Human
(66), (29), (25), (24), (24), (13), (12)
Host
Rabbit
(66), (4), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(46), (23), (20), (16), (14), (12), (12), (8), (5), (1)
Pubmed 4 references available
Catalog no. ABIN350733
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen A synthetic peptide from c-terminal region of mouse Aquaporin 7 (AQP7) conjugated to an immunogenic carrier protein was used as the antigen.
Specificity Specific for SNIP.
Purification whole serum
Alternative Name BNIP3 (BCL2/adenovirus E1B 19 kDa protein-interacting protein 3, NIP3)
Background Function: Apoptosis-inducing protein that, which can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2.
Subcellular location: Mitochondrion membrane, Single-pass membrane protein Potential. Note: Coexpression with the EIB 19-kDa protein results in a shift in NIP3 localization pattern to the nuclear envelope. Also known as: BCL2/adenovirus E1B 19 kDa protein-interacting protein 3, BNIP3, NIP3.
UniProt Q9QWI6
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications. This antibody may also recognise the unphosphorylated form of the BNIP3.
Restrictions For Research Use only
Format Liquid
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term.
Expiry Date 12 months
General Boyd, Malstrom, Subramanian et al.: "Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins." in: Cell, Vol. 79, Issue 2, pp. 341-51, 1994 (PubMed).

Chen, Ray, Dubik et al.: "The E1B 19K/Bcl-2-binding protein Nip3 is a dimeric mitochondrial protein that activates apoptosis." in: The Journal of experimental medicine, Vol. 186, Issue 12, pp. 1975-83, 1998 (PubMed).

Ohi, Tokunaga, Tsunoda et al.: "A novel adenovirus E1B19K-binding protein B5 inhibits apoptosis induced by Nip3 by forming a heterodimer through the C-terminal hydrophobic region." in: Cell death and differentiation, Vol. 6, Issue 4, pp. 314-25, 1999 (PubMed).

Deloukas, Earthrowl, Grafham et al.: "The DNA sequence and comparative analysis of human chromosome 10...." in: Nature, Vol. 429, Issue 6990, pp. 375-81, 2004 (PubMed).

Hosts (66), (4), (1)
Reactivities (66), (29), (25), (24), (24), (13), (12)
Applications (46), (23), (20), (16), (14), (12), (12), (8), (5), (1)
Conjugates (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Epitopes (12), (10), (6), (5), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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