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Details for Product No. ABIN350733

BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (pSer95) antibody

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Antigen
Synonyms NIP3, Nip3
Epitope
»Alternatives pSer95
Reactivity
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 4 references available
Catalog no. ABIN350733
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from the human phospho S95 BNIP3 (BCL2/adenovirus E1B 19 kDa protein-interacting protein 3, NIP3) conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Appears to be specific for BNIP3.
Purity whole serum
Alternative Name BNIP3 (BCL2/adenovirus E1B 19 kDa protein-interacting protein 3, NIP3)
Background Function: Apoptosis-inducing protein that, which can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2.
Subcellular location: Mitochondrion membrane, Single-pass membrane protein Potential. Note: Coexpression with the EIB 19-kDa protein results in a shift in NIP3 localization pattern to the nuclear envelope. Also known as: BCL2/adenovirus E1B 19 kDa protein-interacting protein 3, BNIP3, NIP3.
UniProt Q12983
Application Notes IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. This antibody may also recognise the unphosphorylated form of the BNIP3.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Boyd, Malstrom, Subramanian et al.: "Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins." in: Cell, Vol. 79, Issue 2, pp. 341-51, 1994 (PubMed).

Chen, Ray, Dubik et al.: "The E1B 19K/Bcl-2-binding protein Nip3 is a dimeric mitochondrial protein that activates apoptosis." in: The Journal of experimental medicine, Vol. 186, Issue 12, pp. 1975-83, 1998 (PubMed).

Ohi, Tokunaga, Tsunoda et al.: "A novel adenovirus E1B19K-binding protein B5 inhibits apoptosis induced by Nip3 by forming a heterodimer through the C-terminal hydrophobic region." in: Cell death and differentiation, Vol. 6, Issue 4, pp. 314-25, 1999 (PubMed).

Deloukas, Earthrowl, Grafham et al.: "The DNA sequence and comparative analysis of human chromosome 10." in: Nature, Vol. 429, Issue 6990, pp. 375-81, 2004 (PubMed).

Alternatives for antigen "BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3)", type "Antibodies"
Hosts (66), (4), (1)
Reactivities (67), (32), (26), (25), (24), (14), (12), (2), (1)
Applications (46), (20), (17), (16), (14), (10), (8), (7), (4), (1), (1), (1)
Conjugates (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Epitopes (12), (7), (6), (5), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1)
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