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Details for Product No. ABIN350744

PIM1 (Retinitis Pigmentosa 9 Protein) (Internal Region) antibody

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Antigen
Epitope
Internal Region
Host
Rabbit
Clonality Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN350744
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from the internal region of human PIM1 (Retinitis pigmentosa 9 protein) conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Appears to be specific for PIM1.
Purification Purified
Purity whole serum
Background Function: Is thought to be a target protein for the PIM1 kinase. May play some roles in B-cell proliferation in association with PIM1.Nucleus
Tissue specificity: Appears to be expressed in a wide range of tissues. DISEASE: Defects in RP9 are the cause of retinitis pigmentosa type 9 (RP9). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP9 inheritance is autosomal dominant. Also known as: Retinitis pigmentosa 9 protein, RP9, Pim-1-associated protein, PAP-1.
UniProt Q8TA86
Application Notes IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Keen, Hims, McKie et al.: "Mutations in a protein target of the Pim-1 kinase associated with the RP9 form of autosomal dominant retinitis pigmentosa." in: European journal of human genetics : EJHG, Vol. 10, Issue 4, pp. 245-9, 2002 (PubMed).

Kuroda, Maita, Tabata et al.: "A novel nucleolar protein, PAPA-1, induces growth arrest as a result of cell cycle arrest at the G1 phase." in: Gene, Vol. 340, Issue 1, pp. 83-98, 2004 (PubMed).

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