Pim-1 Oncogene (PIM1) (Internal Region) antibody

Details for Product No. ABIN350744
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Antigen
Synonyms cb1068, fj47b05, pim2, wu:fj47b05, PIM1, pim, pim-1, pim3, LON, LONP, LonHS, PRSS15, hLON, PIM, Pim-1
Epitope
Internal Region
(19), (14), (10), (10), (10), (8), (7), (6), (5), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(138), (64), (63), (37), (37), (36), (24), (24), (1)
Host
Rabbit
(112), (31), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(8), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(89), (71), (50), (30), (16), (16), (11), (6), (5), (1), (1)
Pubmed 2 references available
Quantity 100 μL
Options
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Catalog No. ABIN350744
454.67 $
Plus shipping costs $45.00

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  • +1 404 474 4654
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Immunogen A synthetic peptide from the internal region of human PIM1 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in mouse.
Specificity Specific for PIM1.
Purification Whole serum
Alternative Name PIM1
Background Function: Is thought to be a target protein for the PIM1 kinase. May play some roles in B-cell proliferation in association with PIM1.Nucleus
Tissue specificity: Appears to be expressed in a wide range of tissues. DISEASE: Defects in RP9 are the cause of retinitis pigmentosa type 9 (RP9). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP9 inheritance is autosomal dominant. Also known as: Retinitis pigmentosa 9 protein, RP9, Pim-1-associated protein, PAP-1.
Research Area Cancer, Hematopoietic Progenitors
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
General Keen, Hims, McKie et al.: "Mutations in a protein target of the Pim-1 kinase associated with the RP9 form of autosomal dominant retinitis pigmentosa." in: European journal of human genetics : EJHG, Vol. 10, Issue 4, pp. 245-9, 2002 (PubMed).

Kuroda, Maita, Tabata et al.: "A novel nucleolar protein, PAPA-1, induces growth arrest as a result of cell cycle arrest at the G1 phase." in: Gene, Vol. 340, Issue 1, pp. 83-98, 2004 (PubMed).

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