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Polycystic Kidney Disease 2-Like 2 (PKD2L2) (4th Cytoplasmic Loop) antibody

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Antigen
  • TRPP5
Epitope
4th Cytoplasmic Loop
15
13
11
2
1
Reactivity
Human
21
1
Host
Rabbit
22
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Immunohistochemistry (IHC), Western Blotting (WB)
19
15
2
1
1
1
Supplier
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Immunogen A synthetic peptide from the 4th cytoplasmic loop of human Polycystic kidney disease 2-like 2 protein (PKD2L2, PK2L2, Polycystin-L2) conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Specific for PKD2L2.
Purification Whole serum
Alternative Name PKD2L2 (PKD2L2 Antibody Abstract)
Background Function: May function as a subunit of a cation channel and play a role in fertilization.
Subcellular location: Membrane, Multi-pass membrane protein. Also known as: PKD2L2, PK2L2, Polycystin-L2.
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Stayner, Zhou: "Polycystin channels and kidney disease." in: Trends in pharmacological sciences, Vol. 22, Issue 11, pp. 543-6, 2001 (PubMed).

Guo, Schreiber, Weremowicz, Morton, Lee, Zhou: "Identification and characterization of a novel polycystin family member, polycystin-L2, in mouse and human: sequence, expression, alternative splicing, and chromosomal localization." in: Genomics, Vol. 64, Issue 3, pp. 241-51, 2000 (PubMed).

Veldhuisen, Spruit, Dauwerse, Breuning, Peters: "Genes homologous to the autosomal dominant polycystic kidney disease genes (PKD1 and PKD2)." in: European journal of human genetics : EJHG, Vol. 7, Issue 8, pp. 860-72, 2000 (PubMed).