Polycystic Kidney Disease 2-Like 2 (PKD2L2) (4th Cytoplasmic Loop) antibody

Details for Product No. ABIN350749
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Antigen
Synonyms TRPP5
Epitope
4th Cytoplasmic Loop
(2), (1), (1), (1)
Reactivity
Human, Rat (Rattus), Mouse (Murine)
(5), (1)
Host
Rabbit
(5), (1)
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(6), (2), (1)
Pubmed 3 references available
Catalog no. ABIN350749
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Immunogen A synthetic peptide from the 4th cytoplasmic loop of human Polycystic kidney disease 2-like 2 protein (PKD2L2, PK2L2, Polycystin-L2) conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Specific for SEPT2.
Purification whole serum
Alternative Name PKD2L2
Background Function: May function as a subunit of a cation channel and play a role in fertilization.
Subcellular location: Membrane, Multi-pass membrane protein. Also known as: PKD2L2, PK2L2, Polycystin-L2.
UniProt P42208
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Liquid
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term.
Expiry Date 12 months
General Veldhuisen, Spruit, Dauwerse et al.: "Genes homologous to the autosomal dominant polycystic kidney disease genes (PKD1 and PKD2)." in: European journal of human genetics : EJHG, Vol. 7, Issue 8, pp. 860-72, 2000 (PubMed).

Guo, Schreiber, Weremowicz et al.: "Identification and characterization of a novel polycystin family member, polycystin-L2, in mouse and human: sequence, expression, alternative splicing, and chromosomal localization." in: Genomics, Vol. 64, Issue 3, pp. 241-51, 2000 (PubMed).

Stayner, Zhou: "Polycystin channels and kidney disease." in: Trends in pharmacological sciences, Vol. 22, Issue 11, pp. 543-6, 2001 (PubMed).

Hosts (5), (1)
Reactivities (5), (1)
Applications (6), (2), (1)
Epitopes (2), (1), (1), (1)
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