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Polycystic Kidney Disease 2-Like 2 (PKD2L2) (4th cytoplasmic loop) antibody

Antigen

Polycystic Kidney Disease 2-Like 2 (PKD2L2)

Synonyms PKD2L2, MGC133828
Epitope

4th cytoplasmic loop

Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Human

Application
Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
3 references available
Catalog no. ABIN350749
Quantity 100 µl
Price 413.33 $   Plus shipping costs $35.00
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Additional Information

Alternative name polycystic kidney disease 2-like 2 protein (PKD2L2, PK2L2, Polycystin-L2) (4th cytoplasmic loop)
Swiss-Prot Q9NZM6
Immunogen A synthetic peptide from the 4th cytoplasmic loop of human Polycystic kidney disease 2-like 2 protein (PKD2L2, PK2L2, Polycystin-L2) conjugated to an immunogenic carrier protein was used as the immunogen.
Format Lyophilized
Description FUNCTION: May function as a subunit of a cation channel and play a role in fertilization. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. Also known as: PKD2L2, PK2L2, Polycystin-L2.
Specificity Appears to be specific for PKD2L2.

Application Details

Application Notes IHC, WB. A dilution of 1 : 300 to 1 : 3000 is recommended. The optimal dilution should be determined by the end user.
Purity whole serum
Storage Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Restrictions For Research Use only

Publications

Publications Veldhuisen, Spruit, Dauwerse et al.: "Genes homologous to the autosomal dominant polycystic kidney disease genes (PKD1 and PKD2)." in: European journal of human genetics : EJHG, Vol. 7, Issue 8, pp. 860-72, 2000 (PubMed).

Guo, Schreiber, Weremowicz et al.: "Identification and characterization of a novel polycystin family member, polycystin-L2, in mouse and human: sequence, expression, alternative splicing, and chromosomal localization." in: Genomics, Vol. 64, Issue 3, pp. 241-51, 2000 (PubMed).

Stayner, Zhou: "Polycystin channels and kidney disease." in: Trends in pharmacological sciences, Vol. 22, Issue 11, pp. 543-6, 2001 (PubMed).

Alternatives

Alternatives for antigen "Polycystic Kidney Disease 2-Like 2 (PKD2L2)", type "Antibodies"
Hosts Rabbit (1)
Reactivities Human (1)
Applications Enzyme Immunoassay (EIA) (1), Western Blotting (WB) (1)