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Details for Product No. ABIN350754

Polycystic Kidney Disease 1 Like 1 (PKD1L1) (Extracellular Loop) antibody

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Antigen
Synonyms PRO19563, AA444596
Epitope
»Alternatives Extracellular Loop
Reactivity
»Alternatives Human, Mouse (Murine), Rat (Rattus)
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN350754
Quantity 150 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from the 1t extracellular loop of mouse Polycystic kidney disease protein 1-like 1 (PKD1L1, PK1L1, Polycystin-1L1) conjugated to an immunogenic carrier protein was used as the antigen.
Specificity Specific for AMBRA1.
Purity whole serum
Alternative Name PKD1L1
Background This gene encodes a member of the polycystin protein family containing 11transmembrane domains, a receptor for egg jelly (REJ) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. The encoded protein may play a role in the male reproductive system. Alternative splice variants have been described but their biological nature has not been determined
Function: May have a role in the heart and in the male reproductive system.
Subcellular location: Membrane, Multi-pass membrane protein. Also known as: PKD1L1, Polycystin-1L1, PK1L1.
UniProt Q498S2
Research Area Cancer, Autophagy, Neurogenesis
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
Expiry Date 12 months
Yuasa, Venugopal, Weremowicz et al.: "The sequence, expression, and chromosomal localization of a novel polycystic kidney disease 1-like gene, PKD1L1, in human." in: Genomics, Vol. 79, Issue 3, pp. 376-86, 2002 (PubMed).

Clark, Gurney, Abaya et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).

Alternatives for antigen "Polycystic Kidney Disease 1 Like 1 (PKD1L1)", type "Antibodies"
Hosts (5)
Reactivities (4), (2), (1)
Applications (5), (2), (1)
Epitopes (2), (1), (1)
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