polycystic kidney disease protein 1-like 1 (PKD1L1, PK1L1, Polycystin-1L1) (1st Extracellular Loop) antibody

Antigen: polycystic kidney disease protein 1-like 1 (PKD1L1, PK1L1, Polycystin-1L1)

Binding Site: 1st Extracellular Loop

Clonality: Polyclonal

Host: Rabbit

Reactivity: Mouse (Murine)

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350754

Additional Information

Immunogen: A synthetic peptide from the 1t extracellular loop of mouse Polycystic kidney disease protein 1-like 1 (PKD1L1, PK1L1, Polycystin-1L1) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: This gene encodes a member of the polycystin protein family containing 11transmembrane domains, a receptor for egg jelly (REJ) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. The encoded protein may play a role in the male reproductive system. Alternative splice variants have been described but their biological nature has not been determined FUNCTION: May have a role in the heart and in the male reproductive system. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. Also known as: PKD1L1, Polycystin-1L1, PK1L1.

Specificity: Appears to be specific for PK1L1.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Yuasa, Venugopal, Weremowicz et al.: "The sequence, expression, and chromosomal localization of a novel polycystic kidney disease 1-like gene, PKD1L1, in human." in: Genomics, Vol. 79, Issue 3, pp. 376-86, 2002 (PubMed).

Clark, Gurney, Abaya et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).