Nerve Growth Factor beta Precursor antibody

Antigen: Nerve Growth Factor beta Precursor

Synonyms: NGFB, HSAN5, Beta-NGF, MGC161426, MGC161428, ngfb, ns:zft386, xx:zft386, zgc:109730, NGF, beta-NGF, hsan5, beta-ngf

Clonality: Polyclonal

Host: Sheep

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350773

Additional Information

Alternative name: proNGF (Beta-nerve growth factor precursor, beta-NGF, b-NGF)

Swiss-Prot: P01138

Immunogen: A synthetic peptide from human, rat, mouse, dog proNGF (Beta-nerve growth factor precursor, beta-NGF, b-NGF) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: NGF is a secreted molecule which plays an important roll in the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons. Also known as: Beta-nerve growth factor precursor, beta-NGF, b-NGF.

Specificity: This antiserum appears to be very specific for proNGF.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Publications: Oakey, Howard, Hogarth et al.: "Chromosomal mapping of the high affinity Fc gamma receptor gene." in: Immunogenetics, Vol. 35, Issue 4, pp. 279-82, 1992 (PubMed).

Ieda, Kanazawa, Kimura et al.: "Sema3a maintains normal heart rhythm through sympathetic innervation patterning." in: Nature medicine, Vol. 13, Issue 5, pp. 604-12, 2007 (PubMed).

Arsenijevic, Hernadfalvi, von Meyenburg et al.: "Role for nerve growth factor in the in vivo regulation of glutathione in response to LPS in mice." in: European cytokine network, Vol. 18, Issue 2, pp. 93-101, 2007 (PubMed).

Manni, Di Fausto, Chaldakov et al.: "Brain leptin and nerve growth factor are differently affected by stress in male and female mice: possible neuroendocrine and cardio-metabolic implications." in: Neuroscience letters, Vol. 426, Issue 1, pp. 39-44, 2007 (PubMed).