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RAB5 antibody (RAB5A, Member RAS Oncogene Family) (Internal Region)

Details for Product anti-RAB5A Antibody No. ABIN350782, Supplier: Log in to see
Antigen
  • 2410015H04Rik
  • AI663973
  • AU021172
  • DDBDRAFT_0168594
  • DDBDRAFT_0229401
  • DDB_0168594
  • DDB_0229401
  • nnyRab5a
  • rab5
  • RAB5
  • RAB5A
Epitope
Internal Region
38
28
14
9
8
6
3
3
3
2
2
1
1
1
1
1
1
1
Reactivity
Mouse (Murine), Rat (Rattus)
187
87
77
28
27
11
3
3
3
2
2
2
2
2
2
2
2
2
1
Host
Sheep
148
42
5
3
Clonality
Polyclonal
Conjugate
This RAB5 antibody is un-conjugated
8
8
7
5
4
4
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
175
65
64
64
36
22
18
12
10
2
1
1
Supplier
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Immunogen A synthetic peptide from the internal region of mouse Ras-related protein Rab-5A (RAB5A) conjugated to an immunogenic carrier protein has been used as the immunogen. The antigen is homologous in rat.
Isotype IgG
Specificity Specific for RAB5A.
Alternative Name RAB5A (RAB5A Antibody Abstract)
Background Function: Required for the fusion of plasma membranes and early endosomes.
Enzyme regulation: Regulated by guanine nucleotide exchange factors (GEFs) which promote the
Subcellular location: Cell membrane, Lipid-anchor, Cytoplasmic side. Early endosome membrane, Lipid-anchor. Melanosome. Also known as: RAB5A.
Research Area Signaling
Application Notes Use at a concentration of 10-50 µg/ml.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Yang, Sasaki, Minoshima, Shimizu: "Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway." in: Genomics, Vol. 90, Issue 2, pp. 249-60, 2007 (PubMed).

Carninci, Kasukawa, Katayama, Gough, Frith, Maeda, Oyama, Ravasi, Lenhard, Wells, Kodzius, Shimokawa, Bajic, Brenner, Batalov, Forrest, Zavolan, Davis, Wilming, Aidinis, Allen, Ambesi-Impiombato et al.: "The transcriptional landscape of the mammalian genome. ..." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1559-63, 2005 (PubMed).