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Details for Product No. ABIN350783

RAB5B, Member RAS Oncogene Family (RAB5B) (Internal Region) antibody

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Synonyms C030027M18Rik, zgc:76978
»Alternatives Internal Region
»Alternatives Rabbit
Clonality Polyclonal
»Alternatives Un-conjugated
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 4 references available
Catalog no. ABIN350783
Quantity 100 µL
454.67 $   Plus shipping costs $45.00
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Immunogen A synthetic peptide from the internal part of human Ras-related protein Rab-5B (RAB5B) conjugated to an immunogenic carrier protein has been used as the immunogen. The antigen is homologous in mouse and shares 98% identity with rat.
Specificity Appears to be specific for RAB5B.
Purity whole serum
Alternative Name Ras-related protein Rab-5B (RAB5B)
Background Function: Protein transport. Probably involved in vesicular traffic.
Enzyme regulation: Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP.
Subcellular location: Cell membrane, Lipid-anchor, Cytoplasmic side. Early endosome membrane, Lipid-anchor. Melanosome. Note: Enriched in stage I melanosomes. Also known as: RAB5B.
UniProt P61020
Application Notes IHC, WB. Use at a dilution of 1:300 to 1: 2000. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Wilson, Wilson: "Identification and subcellular localization of human rab5b, a new member of the ras-related superfamily of GTPases." in: The Journal of clinical investigation, Vol. 89, Issue 3, pp. 996-1005, 1992 (PubMed).

Callaghan, Nixon, Bucci et al.: "Direct interaction of EEA1 with Rab5b." in: European journal of biochemistry / FEBS, Vol. 265, Issue 1, pp. 361-6, 1999 (PubMed).

Saito, Murai, Kajiho et al.: "A novel binding protein composed of homophilic tetramer exhibits unique properties for the small GTPase Rab5." in: The Journal of biological chemistry, Vol. 277, Issue 5, pp. 3412-8, 2002 (PubMed).

Chi, Valencia, Hu et al.: "Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes." in: Journal of proteome research, Vol. 5, Issue 11, pp. 3135-44, 2006 (PubMed).

Alternatives for antigen "RAB5B, Member RAS Oncogene Family (RAB5B)", type "Antibodies"
Hosts (22), (2)
Reactivities (23), (21), (17), (15), (14), (14), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Applications (14), (10), (5), (4), (2), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (2), (2), (2), (1), (1), (1)