Ral-A antibody
Reactivity: Human, Mouse, Rat
IHC, WB
Host: Sheep
Polyclonal
unconjugated
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- Target
- Ral-A
- Reactivity
- Human, Mouse, Rat
- Host
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Sheep
- Clonality
- Polyclonal
- Application
- Immunohistochemistry (IHC), Western Blotting (WB)
- Specificity
- Specific for Ral-A.
- Immunogen
- A synthetic peptide from human Ras-related protein Ral-A (Rala, Ral, Ral-a) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
- Isotype
- IgG
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- Application Notes
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A concentration of 10-50 µg/ml is recommended.
The optimal concentration should be determined by the end user.
Not yet tested in other applications. - Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
- Handling Advice
- Avoid freeze and thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
- Expiry Date
- 12 months
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- Target
- Ral-A
- Background
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The product of this gene belongs to the small GTPase superfamily, Ras family of proteins. GTP-binding proteins mediate thetransmembrane signaling initiated by the occupancy of certain cell surface receptors. This gene encodes a low molecular mass ras-like GTP-binding protein that shares about 50% similarity with other ras proteins.
Subunit: Interacts with RALBP1 via its effector domain. Interacts with EXOC8 and EXOC2. EXOC2 and EXOC8 have overlapping binding sites and compete for RALA binding. Interacts with Clostridium exoenzyme C3. Interacts with RALGPS1.
Subcellular location: Cell membrane, Lipid-anchor, Cytoplasmic side. Also known as: Rala, Ral, Ral-a, MGC48949.
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