rala antibody (AA 150-200)

Catalog No. ABIN350790

Product Details anti-rala Antibody

Target: rala (Ras-related Protein Ral-A (rala))

Binding Specificity: AA 150-200

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This rala antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Specificity: Specific for Ral-A.

Immunogen: A synthetic peptide from aa region 150-200 of human RalA conjugated to blue carrier protein was used as the antigen. The antigen is homologous in rat and mouse.

Isotype: IgG

Application Details

Application Notes: A concentration of 10-50 µg/ml is recommended.
The optimal concentration should be determined by the end user.
Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for rala

Target: rala (Ras-related Protein Ral-A (rala))

Alternative Name: RalA (rala Products)

Synonyms: 3010001O15Rik antibody, AW322615 antibody, Ral antibody, Rasl1 antibody, RAL antibody, v-ral simian leukemia viral oncogene A (ras related) antibody, RAS like proto-oncogene A antibody, Rala antibody, RALA antibody

Background: The product of this gene belongs to the small GTPase superfamily, Ras family of proteins. GTP-binding proteins mediate thetransmembrane signaling initiated by the occupancy of certain cell surface receptors. This gene encodes a low molecular mass ras-like GTP-binding protein that shares about 50% similarity with other ras proteins.
Subunit: Interacts with RALBP1 via its effector domain. Interacts with EXOC8 and EXOC2. EXOC2 and EXOC8 have overlapping binding sites and compete for RALA binding. Interacts with Clostridium exoenzyme C3. Interacts with RALGPS1.
Subcellular location: Cell membrane, Lipid-anchor, Cytoplasmic side. Also known as: Rala, Ral, Ral-a, MGC48949.

Pathways: Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome