Retinal G Protein Coupled Receptor (RGR) antibody

Antigen: Retinal G Protein Coupled Receptor (RGR)

Synonyms: RP44, RGR, MGC84794, zgc:110660

Clonality: Polyclonal

Host: Rabbit

Reactivity: Mouse (Murine)

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350792

Additional Information

Swiss-Prot: Q9Z2B3

Immunogen: A synthetic peptide as a part of mouse retinal G protein coupled receptor (RGR) conjugated to immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: FUNCTION: Receptor for all-trans- and 11-cis-retinal. Binds preferentially to the former and may catalyze the isomerization of the chromophore by a retinochrome-like mechanism. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. Also known as: RPE-retinal G protein-coupled receptor, Rgr.

Specificity: Appears to be specific for RGR.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Publications: Tarttelin, Bellingham, Bibb et al.: "Expression of opsin genes early in ocular development of humans and mice." in: Experimental eye research, Vol. 76, Issue 3, pp. 393-6, 2003 (PubMed).

Wenzel, Oberhauser, Pugh et al.: "The retinal G protein-coupled receptor (RGR) enhances isomerohydrolase activity independent of light." in: The Journal of biological chemistry, Vol. 280, Issue 33, pp. 29874-84, 2005 (PubMed).