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RHOU antibody (Internal Region)

RHOU Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN350806
  • Target See all RHOU Antibodies
    RHOU (Ras Homolog Gene Family, Member U (RHOU))
    Binding Specificity
    • 15
    • 5
    • 4
    • 2
    • 1
    • 1
    Internal Region
    Reactivity
    • 21
    • 19
    • 17
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 34
    • 1
    Rabbit
    Clonality
    • 36
    Polyclonal
    Conjugate
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This RHOU antibody is un-conjugated
    Application
    • 21
    • 13
    • 13
    • 11
    • 6
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificity
    Specific for RhoU.
    Cross-Reactivity
    Human, Mouse, Rat
    Cross-Reactivity (Details)
    Other species not yet tested.
    Purification
    IgG
    Immunogen
    A synthetic peptide from the internal region of human Rho related GTP binding protein RhoU (CDC42 like GTPase 1, CDC42L1, Ryu GTPase) conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 90% identity with rat and mouse sequence.
    Isotype
    IgG
    Top Product
    Discover our top product RHOU Primary Antibody
  • Application Notes
    IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
    Handling Advice
    Avoid freeze and thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Expiry Date
    12 months
  • Target
    RHOU (Ras Homolog Gene Family, Member U (RHOU))
    Alternative Name
    RhoU (RHOU Products)
    Synonyms
    ARHU antibody, CDC42L1 antibody, DJ646B12.2 antibody, WRCH1 antibody, fJ646B12.2 antibody, hG28K antibody, 2310026M05Rik antibody, AI182090 antibody, Arhu antibody, G28K antibody, WRCH-1 antibody, mG28K antibody, arhu antibody, hg28k antibody, wrch1 antibody, wrch-1 antibody, cdc42l1 antibody, MGC107947 antibody, fj646b12.2 antibody, zgc:101642 antibody, wu:fb18g01 antibody, zgc:110357 antibody, Wrch antibody, rac-2 antibody, rhou antibody, xg28k antibody, ras homolog family member U antibody, ras homolog gene family, member U antibody, ras homolog family member Ua antibody, ras homolog family member Ub antibody, ras homolog family member U L homeolog antibody, RHOU antibody, Rhou antibody, rhou antibody, rhoua antibody, rhoub antibody, rhou.L antibody
    Background
    Function: Acts upstream of PAK1 to regulate the actin cytoskeleton, adhesion turnover and increase cell migration. Stimulates quiescent cells to reenter the cell cycle. Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP-bound. Subcellular location: Cell membrane, Lipid-anchor, Cytoplasmic side. Golgi apparatus membrane, Lipid-anchor. Cell junction âÄ° focal adhesion. Cell projection âÄ° podosome. Note: Localizes to podosomes in SRC-transformed cells. Tissue specificity: Ubiquitously expressed in all tissues examined. Expressed at high levels in the stomach, small intestine, brain, skeletal muscle and placenta.,Rho Family,Rho related GTP binding protein RhoU, RhoU, Ryu GTPase, CDC42-like GTPase 1, Rho GTPase-like protein ARHU, GTP-binding protein-like 1, ARHU, CDC42L1, G28K, WRCH1, Wnt-1 responsive Cdc42 homolog 1
    UniProt
    Q7L0Q8
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