serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 10 (SERPINA10) (N-Term) antibody

Antigen: serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 10 (SERPINA10)

Synonyms: PZI, ZPI, Rasp1, MGC108600, MGC25863, SERPINA10, MGC159637, DKFZp469K045

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Conjugate: Un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350830

Additional Information

Alternative name: Serpin A10 (SERPINA10)

UniProt: Q9UK55

Immunogen: A synthetic peptide from n-terminal region of human Serpin A10 (SERPINA10) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: FUNCTION: Inhibits factor Xa activity in the presence of protein Z, calcium and phospholipid. Subcellular location: Secreted Tissue specificity: Expressed by the liver and secreted in plasma. Also known as: Protein Z-dependent protease inhibitor, PZ-dependent protease inhibitor, PZI, SERPINA10, ZPI.

Specificity: Appears to be specific for Serpin A10.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Han, Fiehler, Broze: "Isolation of a protein Z-dependent plasma protease inhibitor." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 16, pp. 9250-5, 1998 (PubMed).

Han, Huang, Fiehler et al.: "The protein Z-dependent protease inhibitor is a serpin." in: Biochemistry, Vol. 38, Issue 34, pp. 11073-8, 1999 (PubMed).

Clark, Gurney, Abaya et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).

Liu, Qian, Gritsenko et al.: "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry." in: Journal of proteome research, Vol. 4, Issue 6, pp. 2070-80, 2005 (PubMed).

Chen, Jiang, Sun et al.: "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry." in: Journal of proteome research, Vol. 8, Issue 2, pp. 651-61, 2009 (PubMed).