SRCIN1 antibody (SRC Kinase Signaling Inhibitor 1) (N-Term)

Details for Product anti-SRCIN1 Antibody No. ABIN350837, Supplier: Log in to see
  • P140
  • SNIP
  • mKIAA1684
  • p140Cap
  • Snip
  • novel protein similar to vertebrate SNAP25-interacting protein (SNIP)
  • SNAP25-interacting protein
  • SRC kinase signaling inhibitor 1
  • LOC565863
  • LOC100353870
  • SRCIN1
  • Srcin1
Rat (Rattus), Mouse (Murine), Human
Immunohistochemistry (IHC), Western Blotting (WB)
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Immunogen A synthetic peptide from the n-terminal of human SNIP conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
Specificity Specific for SNIP.
Purification Whole serum
Alternative Name SNIP (SRCIN1 Antibody Abstract)
Background Function: Delays the onset of cell spreading in the early stages of cell adhesion to fibronectin. Also involved in calcium-dependent exocytosis from PC12 cells.
Subunit: Interacts with the N-terminal coiled-coil region ofSNAP25. Interacts with BCAR1/p130Cas through its C-terminal domain.
Subcellular location: Cytoplasm. Cytoplasm, cytoskeleton. Note: Localized to the perinuclear region, lamellopodia, cortical actin and actin stress fibers but not to focal adhesions. Also known as: p130 Cas associated protein, p140 Cap,SNAP 25 interacting protein, P140.
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Supplier Images
 image for anti-SRCIN1 antibody (SRC Kinase Signaling Inhibitor 1) (N-Term) (ABIN350837) IF on 1 day- old mouse cortical cell culture using Rabbit antibody to n-terminal of S...
 image for anti-SRCIN1 antibody (SRC Kinase Signaling Inhibitor 1) (N-Term) (ABIN350837) IF on 1 day- old mouse cortical cell culture using Rabbit antibody to n-terminal of S...
Background publications Munton, Tweedie-Cullen, Livingstone-Zatchej, Weinandy, Waidelich, Longo, Gehrig, Potthast, Rutishauser, Gerrits, Panse, Schlapbach, Mansuy: "Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 2, pp. 283-93, 2007 (PubMed).

DeGiorgis, Jaffe, Moreira, Carlotti, Leite, Pant, Dosemeci: "Phosphoproteomic analysis of synaptosomes from human cerebral cortex." in: Journal of proteome research, Vol. 4, Issue 2, pp. 306-15, 2005 (PubMed).

Di Stefano, Cabodi, Boeri Erba, Margaria, Bergatto, Giuffrida, Silengo, Tarone, Turco, Defilippi: "P130Cas-associated protein (p140Cap) as a new tyrosine-phosphorylated protein involved in cell spreading." in: Molecular biology of the cell, Vol. 15, Issue 2, pp. 787-800, 2004 (PubMed).

Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Nagase, Kikuno, Hattori, Kondo, Okumura, Ohara: "Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 7, Issue 6, pp. 347-55, 2001 (PubMed).