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Details for Product No. ABIN350843

Superoxide Dismutase 3, Extracellular (SOD3) (AA 10-50) antibody

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Antigen
Synonyms EC-SOD, AI314465, ECSOD, ECSODPT, SOD3, LOC780439, fb05f10, si:dkey-117m1.6, sod3, wu:fb05f10
Epitope
»Alternatives AA 10-50
Reactivity
»Alternatives Rat (Rattus), Mouse (Murine)
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN350843
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from AA 10-50 of human SOD3 conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Specific for WFS1.
Purity whole serum
Alternative Name SOD3
Background Function: Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen.
Catalytic activity: 2 superoxide + 2 H(+) = O(2) + H(2)O(2).
Tissue specificity: Expressed in blood vessels, heart, lungs, kidney and placenta. Major SOD isoenzyme in extracellular fluids such as plasma, lymph and synovial fluid.
Subcellular location: Secreted › extracellular space. Note: 99% of EC-SOD is anchored to heparan sulfate proteoglycans in the tissue interstitium, and 1% is located in the vasculature in equilibrium between the plasma and the endothelium. Also known as: Superoxide dismutase 3, SODE, SOD E.
UniProt P56695
Application Notes A dilution of 1: 300 to 1: 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
Expiry Date 12 months
Adachi, Ohta, Hayashi et al.: "The site of nonenzymic glycation of human extracellular-superoxide dismutase in vitro." in: Free radical biology & medicine, Vol. 13, Issue 3, pp. 205-10, 1992 (PubMed).

Hjalmarsson, Marklund, Engstroem et al.: "Isolation and sequence of complementary DNA encoding human extracellular superoxide dismutase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 84, Issue 18, pp. 6340-4, 1987 (PubMed).

Folz, Crapo: "Extracellular superoxide dismutase (SOD3): tissue-specific expression, genomic characterization, and computer-assisted sequence analysis of the human EC SOD gene." in: Genomics, Vol. 22, Issue 1, pp. 162-71, 1994 (PubMed).

Adachi, Morihara, Yamazaki et al.: "An arginine-213 to glycine mutation in human extracellular-superoxide dismutase reduces susceptibility to trypsin-like proteinases." in: Journal of biochemistry, Vol. 120, Issue 1, pp. 184-8, 1997 (PubMed).

Nozik-Grayck, Suliman, Piantadosi: "Extracellular superoxide dismutase." in: The international journal of biochemistry & cell biology, Vol. 37, Issue 12, pp. 2466-71, 2005 (PubMed).

Alternatives for antigen "Superoxide Dismutase 3, Extracellular (SOD3)", type "Antibodies"
Hosts (48), (20), (2), (2)
Reactivities (61), (29), (21), (12), (12), (12)
Applications (60), (42), (20), (18), (12), (10), (8), (6), (6), (4), (3), (2), (1)
Conjugates (7), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (7), (6), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1)
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