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Sorting Nexin 2 (Nexin-2, SNX2, TRG9) (C-Term) antibody

Details for Product No. ABIN350874
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Antigen
Epitope
C-Term
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 5 references available
Quantity 100 µL
Options
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Availability Will be delivered in 7 to 8 Business Days
Catalog No. ABIN350874
454.67 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen A synthetic peptide from the c-terminal of human Sorting Nexin-2 conjugated to an immunogenic carrier protein was used as the antigen. The antigen is homologous in rat and mouse.
Specificity Specific for KCNJ4.
Purification whole serum
Background Function: May be involved in several stages of intracellular trafficking. Component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also known as: Nexin-2, SNX2, Transformation-related gene 9 protein, TRG-9, TRG9.
UniProt P52189
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not tested in other applications.
Restrictions For Research Use only
Format Liquid
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term.
Expiry Date 12 months
General Haft, de la Luz Sierra, Barr et al.: "Identification of a family of sorting nexin molecules and characterization of their association with receptors." in: Molecular and cellular biology, Vol. 18, Issue 12, pp. 7278-87, 1998 (PubMed).

Fuchs, Rehkamp, Haas et al.: "The human formin-binding protein 17 (FBP17) interacts with sorting nexin, SNX2, and is an MLL-fusion partner in acute myelogeneous leukemia." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 15, pp. 8756-61, 2001 (PubMed).

Beausoleil, Jedrychowski, Schwartz et al.: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, 2004 (PubMed).

Beausoleil, Villén, Gerber et al.: "A probability-based approach for high-throughput protein phosphorylation analysis and site localization." in: Nature biotechnology, Vol. 24, Issue 10, pp. 1285-92, 2006 (PubMed).

Dephoure, Zhou, Villén et al.: "A quantitative atlas of mitotic phosphorylation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 31, pp. 10762-7, 2008 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN350874
454.67 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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