Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN350885

SUMO2SUMO3 (Small Ubiquitin-Related Modifier 2 and 3) (N-Term) antibody

Request
Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Epitope
»Alternatives N-Term
Reactivity
»Alternatives Rat (Rattus), Mouse (Murine), Human
Host
»Alternatives Sheep
Clonality Polyclonal
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN350885
Quantity 500 µg
Price
454.67 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from the n-terminal of rat SUMO2 & SUMO3 (Small ubiquitin-related modifier 2 and 3) conjugated to an immunogenic carrier protein was used as the antigen. The antigen is homologous in many species including human, mouse and chicken.
Isotype IgG
Specificity Specific for TrkC.
Purity whole serum
Background Function: Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4
Subcellular location: Nucleus Also known as: Small ubiquitin-related modifier 2, SUMO-2, Ubiquitin-like protein SMT3B, SMT3 homolog 2, Sentrin-2, Smt3b, Smt3h2, SUMO-3, SUMO 3, Small ubiquitin-related modifier 3.
UniProt Q6VNS1
Research Area Cancer
Application Notes A dilution of 1: 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
Expiry Date 12 months
Chen, Mannen, Li: "Characterization of mouse ubiquitin-like SMT3A and SMT3B cDNAs and gene/pseudogenes." in: Biochemistry and molecular biology international, Vol. 46, Issue 6, pp. 1161-74, 1999 (PubMed).

Carninci, Kasukawa, Katayama et al.: "The transcriptional landscape of the mammalian genome." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1559-63, 2005 (PubMed).

Rosendorff, Sakakibara, Lu et al.: "NXP-2 association with SUMO-2 depends on lysines required for transcriptional repression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 14, pp. 5308-13, 2006 (PubMed).

Zody, Garber, Adams et al.: "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." in: Nature, Vol. 440, Issue 7087, pp. 1045-9, 2006 (PubMed).

Baba, Maita, Jee et al.: "Crystal structure of SUMO-3-modified thymine-DNA glycosylase." in: Journal of molecular biology, Vol. 359, Issue 1, pp. 137-47, 2006 (PubMed).

Alternatives for antigen "SUMO2SUMO3 (Small Ubiquitin-Related Modifier 2 and 3)", type "Antibodies"
Hosts (1)
Reactivities (1), (1), (1)
Applications (1), (1)
Epitopes (1)
Beacon