Synaptophysin (SYP) antibody

Antigen: Synaptophysin (SYP)

Synonyms: Syn, p38, AI848995, A230093K24Rik, Syp1, syp-A, xsypi, MGC86277, syp-B, xsypii, MGC86267

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350896

Additional Information

Swiss-Prot: P08247

Immunogen: A synthetic peptide as a part of human Synaptophysin (SYP) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: Synaptophysin (p38) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells. FUNCTION: Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Also known as: SYP.

Specificity: Appears to be specific for Synaptophysin.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Publications: Ozucelik, Lafreniere, Archer et al.: "Synaptophysin: structure of the human gene and assignment to the X chromosome in man and mouse." in: American journal of human genetics, Vol. 47, Issue 3, pp. 551-61, 1990 (PubMed).

Suedhof, Lottspeich, Greengard et al.: "The cDNA and derived amino acid sequences for rat and human synaptophysin." in: Nucleic acids research, Vol. 15, Issue 22, pp. 9607, 1988 (PubMed).

Fisher, Ciccodicola, Tanaka et al.: "Sequence-based exon prediction around the synaptophysin locus reveals a gene-rich area containing novel genes in human proximal Xp." in: Genomics, Vol. 45, Issue 2, pp. 340-7, 1998 (PubMed).