Add to Basket Bulk discount
Order hotline:
+1 404 474 4654
+1 888 205 9894 (TF)

Synaptosomal-Associated Protein, 25kDa (SNAP25) antibody

Antigen

Synaptosomal-Associated Protein, 25kDa (SNAP25)
Synonyms RIC4, SEC9, SNAP, RIC-4, SNAP-25, FLJ23079, bA416N4.2, dJ1068F16.2, ric4, sec9, ric-4, snap-25, MGC68863, SNAP25, MGC139754, DKFZp459B0611, DKFZp459G0410, sp, Bdr, SNAP-25B, MGC105414, snap25
Clonality Polyclonal
Host
Alternatives

Sheep
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
5 references available
Catalog no. ABIN350902
Quantity 500 µg  (Variants)
Price 454.67 $   Plus shipping costs $45.00
Bulk discount
Shipping to
Availability Will be delivered in 7 to 8 Business Days

Additional Information
Application Details Publications Alternatives Variants back to top

Alternative name Synaptosomal associated protein 25 (SNAP-25,SNAP25)
UniProt P60880
Immunogen A synthetic peptidefrom human Synaptosomal associated protein 25 (SNAP-25, SNAP25, SEC9) conjugated to an immunogenic carrier protein was used as the immunogen.
Format Lyophilized
Isotype IgG
Description FUNCTION: t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. SUBUNIT: Part of the SNARE core complex containingSNAP25, VAMP2 and STX1A. This complex binds CPLX1. Interacts with TRIM9, RIMS1,SNAP25BP and HGS. Binds STXBP6. Found in a ternary complex with STX1A and VAMP8. Found in a complex containing SYT1, SV2B and syntaxin-1. SUBCELLULAR LOCATION: Membrane; Lipid-anchor. Cell junction, synapse, synaptosome. Note: Membrane association requires palmitoylation. TISSUE SPECIFICITY: Neurons of the neocortex, hippocampus, piriform cortex, anterior thalamic nuclei, pontine nuclei, and granule cells of the cerebellum. Also known as:SNAP-25, Synaptosomal-associated 25 kDa protein,SNAP25, RIC4, SEC9,SNAP, RIC-4, Super protein, SUP.
Specificity Appears to be specific for SNAP-25.

Application Details
Publications Alternatives Variants back to top

Application Notes IHC, WB. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
Purity IgG
Storage Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Restrictions For Research Use only

Publications
Application Details Alternatives Variants back to top

Zhao, Hashida, Takahashi et al.: "Cloning and sequence analysis of the human SNAP25 cDNA." in: Gene, Vol. 145, Issue 2, pp. 313-4, 1994 (PubMed).

Bark, Wilson: "Human cDNA clones encoding two different isoforms of the nerve terminal protein SNAP-25." in: Gene, Vol. 139, Issue 2, pp. 291-2, 1994 (PubMed).

Jagadish, Fernandez, Hewish et al.: "Insulin-responsive tissues contain the core complex protein SNAP-25 (synaptosomal-associated protein 25) A and B isoforms in addition to syntaxin 4 and synaptobrevins 1 and 2." in: The Biochemical journal, Vol. 317 ( Pt 3), pp. 945-54, 1996 (PubMed).

Deloukas, Matthews, Ashurst et al.: "The DNA sequence and comparative analysis of human chromosome 20." in: Nature, Vol. 414, Issue 6866, pp. 865-71, 2002 (PubMed).

Chen, Tomchick, Kovrigin et al.: "Three-dimensional structure of the complexin/SNARE complex." in: Neuron, Vol. 33, Issue 3, pp. 397-409, 2002 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "Synaptosomal-Associated Protein, 25kDa (SNAP25)", type "Antibodies"
Hosts Rabbit (59), Mouse (57), Goat (13), Sheep (5)
Reactivities Human (111), Mouse (Murine) (59), Rat (Rattus) (57), Cow (Bovine) (29), Chicken (25), Pig (Porcine) (7), Dog (Canine) (5), Monkey (5), Cat (Feline) (3), Hamster (2), Zebrafish (Danio rerio) (2), Guinea Pig (1), Insect (1), Mammalian (1), Rabbit (1), Xenopus laevis (1), Zebrafish (1)
Applications Western Blotting (WB) (97), ELISA (63), Immunofluorescence (IF) (36), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (33), Immunohistochemistry (IHC) (29), Flow Cytometry (FACS) (15), Immunohistochemistry (Fixed) (IHC (fx)) (6), Immunoprecipitation (IP) (6), Immunocytochemistry (ICC) (5), Immunohistochemistry (Frozen Sections) (IHC (fro)) (5), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Dot Blot (DB) (2), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes C-Term (35), AA 1-206 (3), AA 183-197 (2), AA 195-206 (1), Cleaved, AA 183-197 (1), Cleaved, Uncleaved, AA 183-197 (1), Internal Region,AA 35-63 (1), Whole Molecule (1), cleaved (1), pThr138 (1)