Synaptotagmin XII (SYT12) (C-Term) antibody

Details for Product No. ABIN350912
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms SYT11, sytXII, Srg1, zgc:194750, zgc:194771, DKFZp459J0427
Epitope
C-Term
(2), (2), (1)
Reactivity
Human
(20), (18), (18), (12), (12), (2)
Host
Rabbit
(20), (4)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(15), (10), (5), (4), (3), (2), (1)
Pubmed 3 references available
Catalog no. ABIN350912
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
Options
Shipping to United States (Change)
Availability Will be delivered in 7 to 8 Business Days

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen A synthetic peptide from the c-terminal of human Synaptotagmin 12 conjugated to an immunogenic carrier protein was used as the antigen. The antigen is homologous in rat, mouse.
Specificity Specific for KCNJ5.
Purification whole serum
Alternative Name Synaptotagmin 12 (SYT12, Synaptotagmin XII)
Background Function: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.
Subcellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane, Single-pass membrane protein. Also known as: Synaptotagmin-12, SYT12, SYT-12, Synaptotagmin XII, SytXII.
UniProt P48545
Research Area Cardiovascular, Metabolism
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Liquid
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term.
Expiry Date 12 months
Supplier Images
anti-Synaptotagmin XII (SYT12) (C-Term) antibody IF on 1 day- old mouse cortical cell culture using Rabbit antibody to c-terminal of Synaptotagmin 12 (SYT12, Synaptotagmin XII): whole serum at 1: 2000 dilution. DAPI counter stained.
anti-Synaptotagmin XII (SYT12) (C-Term) antibody (2) IF on 1 day- old mouse cortical cell culture using Rabbit antibody to c-terminal of Synaptotagmin 12 (SYT12, Synaptotagmin XII): whole serum at 1: 2000 dilution. DAPI counter stained appearing in blue.
General Thompson: "Thyroid hormone-responsive genes in developing cerebellum include a novel synaptotagmin and a hairless homolog." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 16, Issue 24, pp. 7832-40, 1997 (PubMed).

Fukuda, Kanno, Ogata et al.: "Mechanism of the SDS-resistant synaptotagmin clustering mediated by the cysteine cluster at the interface between the transmembrane and spacer domains." in: The Journal of biological chemistry, Vol. 276, Issue 43, pp. 40319-25, 2001 (PubMed).

Carninci, Kasukawa, Katayama et al.: "The transcriptional landscape of the mammalian genome...." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1559-63, 2005 (PubMed).

Hosts (20), (4)
Reactivities (20), (18), (18), (12), (12), (2)
Applications (15), (10), (5), (4), (3), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (2), (2), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
back to top