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Details for Product No. ABIN350928

Synaptotagmin V (SYT5) antibody

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SytV, SytIX, CG13462, CG3020, CG42333, Dmel\\CG42333, Dmel_CG13462, Dmel_CG3020, Syt V, Syt beta, Syt13, dsytbeta, syt13, sytbeta, syt5, zgc:92682, ARABIDOPSIS THALIANA SYNAPTOTAGMIN HOMOLOG E, ATSYTE ... show more
»Alternatives Rat (Rattus), Mouse (Murine)
»Alternatives Rabbit
Clonality Polyclonal
»Alternatives Un-conjugated
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 6 references available
Catalog no. ABIN350928
Quantity 100 µL
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide as a part of rat, mouse Synaptotagmin-5 (Synaptotagmin V, SytV, Synaptotagmin IX, Syt5) conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Appears to be specific for SYT5.
Purity whole serum
Alternative Name Synaptotagmin-5 (Synaptotagmin V, SytV, Synaptotagmin IX, Syt5)
Background Function: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca(2+)-dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface.
Cofactor: Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.
Subunit: Homodimer. Can also form heterodimers. Interacts with both alpha- and beta-tubulin.
Subcellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane, Multi-pass membrane protein. Recycling endosome membrane, Multi-pass membrane protein. Note: In mast cells, localizes to the endocytic recycling compartment. Also known as: Synaptotagmin 5, Synaptotagmin V, SytV, Synaptotagmin IX, Syt5.
UniProt P47861
Application Notes IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Hudson, Birnbaum: "Identification of a nonneuronal isoform of synaptotagmin." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 13, pp. 5895-9, 1995 (PubMed).

Craxton, Goedert: "Synaptotagmin V: a novel synaptotagmin isoform expressed in rat brain." in: FEBS letters, Vol. 361, Issue 2-3, pp. 196-200, 1995 (PubMed).

Fukuda, Kanno, Mikoshiba: "Conserved N-terminal cysteine motif is essential for homo- and heterodimer formation of synaptotagmins III, V, VI, and X." in: The Journal of biological chemistry, Vol. 274, Issue 44, pp. 31421-7, 1999 (PubMed).

Fukuda, Kowalchyk, Zhang et al.: "Synaptotagmin IX regulates Ca2+-dependent secretion in PC12 cells." in: The Journal of biological chemistry, Vol. 277, Issue 7, pp. 4601-4, 2002 (PubMed).

Haberman, Grimberg, Fukuda et al.: "Synaptotagmin IX, a possible linker between the perinuclear endocytic recycling compartment and the microtubules." in: Journal of cell science, Vol. 116, Issue Pt 21, pp. 4307-18, 2003 (PubMed).

Ballif, Carey, Sunyaev et al.: "Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain." in: Journal of proteome research, Vol. 7, Issue 1, pp. 311-8, 2008 (PubMed).

Alternatives for antigen "Synaptotagmin V (SYT5)", type "Antibodies"
Hosts (20), (2), (1)
Reactivities (22), (14), (13), (13), (13), (13), (12)
Applications (12), (10), (4), (4), (2), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (3), (2), (2), (1), (1), (1)