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Syntaxin 16 (STX16) antibody

Details for Product No. ABIN350934, Supplier: Log in to see
Antigen
  • CG1467
  • Dm Syx16
  • DmSyx16
  • Dmel\\CG1467
  • SYX16
  • Syx
  • dSyx 16
  • dSyx16
  • syntaxin-16
  • stx16
  • stx16a
  • syn16
  • STX16
  • im:7158627
  • ACYPI005518
  • 4930401D03
  • 5430410K23Rik
  • 6330500A18Rik
  • AI648908
  • AW553605
  • Syn16
  • SYN16
Reactivity
Mouse (Murine)
40
11
8
2
Host
Rabbit
34
5
2
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Immunohistochemistry (IHC)
37
25
16
7
2
1
1
Supplier
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Immunogen A synthetic peptide from mouse Syntaxin-16 (Syntaxin 16, STX16, Syn16) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in chicken, orangutan and pig.
Specificity Specific for Syntaxin-16.
Purification Whole serum
Alternative Name Syntaxin 16 (STX16 Antibody Abstract)
Background Function: SNARE involved in a vesicular transport step within the Golgi stack.
Subcellular location: Golgi apparatus membrane, Single-pass type IV membrane protein.
Subcellular location: Isoform C: Cytoplasm.
Tissue specificity: Ubiquitous. DISEASE: Genetic variations in STX16 may be a cause of pseudohypoparathyroidism type 1B (PHP1B) Pseudohypoparathyroidism refers to a heterogeneous group of disorders characterized by resistance to parathyroid hormone (PTH). PHP1B is characterized by PTH-resistant hypocalcemia and hyperphosphatemia. Patients affected with PHP1B lack developmental defects characteristic of Albright hereditary osteodystrophy, and typically show no other endocrine abnormalities besides resistance to PTH. In some cases microdeletions involving STX16 appear to cause loss of methylation at exon A/B of the GNAS gene, resulting in PHP1B. Also known as: Syntaxin 16, STX16, Syn16.
Research Area Organelles
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Supplier Images
 image for anti-Syntaxin 16 (STX16) antibody (ABIN350934) IF on 1 day- old mouse cortical cell culture using Rabbit antibody to mouse, chicken,...
 image for anti-Syntaxin 16 (STX16) antibody (ABIN350934) IHC on rat brain (striatum) using Rabbit antibody to mouse, chicken, orangutan, pig S...
 image for anti-Syntaxin 16 (STX16) antibody (ABIN350934) IF on 1 day- old mouse cortical cell culture using Rabbit antibody to mouse, chicken,...
Background publications Munton, Tweedie-Cullen, Livingstone-Zatchej et al.: "Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 2, pp. 283-93, 2007 (PubMed).

Carninci, Kasukawa, Katayama et al.: "The transcriptional landscape of the mammalian genome. ..." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1559-63, 2005 (PubMed).