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Details for Product No. ABIN350935

Syntaxin 16 (STX16) antibody

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SYN16, Syn16, AI648908, AW553605, 4930401D03, 5430410K23Rik, 6330500A18Rik, CG1467, Dm Syx16, DmSyx16, Dmel\\CG1467, SYX16, Syx, dSyx 16, dSyx16, syntaxin-16, stx16, stx16a, syn16, STX16, im:7158627,  ... show more
»Alternatives Human
»Alternatives Rabbit
Clonality Polyclonal
»Alternatives Immunohistochemistry (IHC)
Pubmed 5 references available
Catalog no. ABIN350935
Quantity 100 µL
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide as a part of human Syntaxin-16 (Syntaxin 16, STX16, Syn16) conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Appears to be specific for Syntaxin-16.
Purity whole serum
Alternative Name Syntaxin-16 (Syntaxin 16, STX16, Syn16)
Background Function: SNARE involved in a vesicular transport step within the Golgi stack.
Subcellular location: Golgi apparatus membrane, Single-pass type IV membrane protein.
Subcellular location: Isoform C: Cytoplasm.
Tissue specificity: Ubiquitous. DISEASE: Genetic variations in STX16 may be a cause of pseudohypoparathyroidism type 1B (PHP1B) Pseudohypoparathyroidism refers to a heterogeneous group of disorders characterized by resistance to parathyroid hormone (PTH). PHP1B is characterized by PTH-resistant hypocalcemia and hyperphosphatemia. Patients affected with PHP1B lack developmental defects characteristic of Albright hereditary osteodystrophy, and typically show no other endocrine abnormalities besides resistance to PTH. In some cases microdeletions involving STX16 appear to cause loss of methylation at exon A/B of the GNAS gene, resulting in PHP1B. Also known as: Syntaxin 16, STX16, Syn16.
UniProt O14662
Application Notes IHC. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Tang, Low, Lee et al.: "Molecular cloning and localization of human syntaxin 16, a member of the syntaxin family of SNARE proteins." in: Biochemical and biophysical research communications, Vol. 242, Issue 3, pp. 673-9, 1998 (PubMed).

Simonsen, Bremnes, Ruonning et al.: "Syntaxin-16, a putative Golgi t-SNARE." in: European journal of cell biology, Vol. 75, Issue 3, pp. 223-31, 1998 (PubMed).

Deloukas, Matthews, Ashurst et al.: "The DNA sequence and comparative analysis of human chromosome 20." in: Nature, Vol. 414, Issue 6866, pp. 865-71, 2002 (PubMed).

Bastepe, Froehlich, Hendy et al.: "Autosomal dominant pseudohypoparathyroidism type Ib is associated with a heterozygous microdeletion that likely disrupts a putative imprinting control element of GNAS." in: The Journal of clinical investigation, Vol. 112, Issue 8, pp. 1255-63, 2003 (PubMed).

Linglart, Gensure, Olney et al.: "A novel STX16 deletion in autosomal dominant pseudohypoparathyroidism type Ib redefines the boundaries of a cis-acting imprinting control element of GNAS." in: American journal of human genetics, Vol. 76, Issue 5, pp. 804-14, 2005 (PubMed).

Alternatives for antigen "Syntaxin 16 (STX16)", type "Antibodies"
Hosts (15), (3), (1)
Reactivities (16), (6), (5), (2), (1), (1), (1)
Applications (16), (7), (5), (3), (2), (1), (1), (1), (1), (1)
Epitopes (6), (2), (2), (1), (1)