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Syntaxin 6 (STX6) antibody

Details for Product No. ABIN350937, Supplier: Log in to see
Antigen
  • CG7736
  • CT23545
  • Dm Syx6
  • DmSyx6
  • Dmel\\CG7736
  • SYN6
  • SYX6/10
  • Syx
  • MGC78971
  • MGC132090
  • STX6
  • fb51b08
  • wu:fb51b08
  • zgc:110658
  • si:dkey-121a11.2
  • LOC734102
  • Syx6
  • Bmsyx6
  • Syntaxin-6
  • 2310039E05Rik
  • 2410005I16Rik
  • AA437559
  • AI415714
  • AI845861
Reactivity
Rat (Rattus), Mouse (Murine)
82
29
26
18
5
3
2
2
1
1
1
Host
Rabbit
71
16
13
2
Clonality
Polyclonal
Conjugate
Un-conjugated
12
12
11
3
3
3
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
80
57
13
11
11
9
5
2
1
Supplier
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Immunogen A synthetic peptide from mouse Syntaxin-6 (Stx6, Syntaxin 6) conjugated to an immunogenic carrier protein was used as the antigen.
Specificity Specific for Syntaxin-6.
Purification Whole serum
Alternative Name Syntaxin 6 (STX6 Antibody Abstract)
Background Function: Involved in intracellular vesicle trafficking.
Subunit: Binds EEA1. Interacts with VPS45A and GOPC. Interacts with MARCH2 and MARCH3. Identified in a complex containing STX6, STX13, VAMP4 and VTI1A.
Subcellular location: Golgi apparatus membrane, Single-pass type IV membrane protein. Also known as: Syntaxin-6, Stx6, Syntaxin 6.
Research Area Signaling
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Fukuda, Nakamura, Hirose: "MARCH-III Is a novel component of endosomes with properties similar to those of MARCH-II." in: Journal of biochemistry, Vol. 139, Issue 1, pp. 137-45, 2006 (PubMed).

Carninci, Kasukawa, Katayama et al.: "The transcriptional landscape of the mammalian genome. ..." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1559-63, 2005 (PubMed).

Nakamura, Fukuda, Kato et al.: "MARCH-II is a syntaxin-6-binding protein involved in endosomal trafficking." in: Molecular biology of the cell, Vol. 16, Issue 4, pp. 1696-710, 2005 (PubMed).

Misura, Bock, Gonzalez et al.: "Three-dimensional structure of the amino-terminal domain of syntaxin 6, a SNAP-25 C homolog." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 14, pp. 9184-9, 2002 (PubMed).

Simonsen, Gaullier, DArrigo et al.: "The Rab5 effector EEA1 interacts directly with syntaxin-6." in: The Journal of biological chemistry, Vol. 274, Issue 41, pp. 28857-60, 1999 (PubMed).

Bock, Lin, Scheller: "A new syntaxin family member implicated in targeting of intracellular transport vesicles." in: The Journal of biological chemistry, Vol. 271, Issue 30, pp. 17961-5, 1996 (PubMed).