Syntaxin 6 (STX6) antibody

Antigen: Syntaxin 6 (STX6)

Synonyms: MGC93348, CT23545, Dm Syx6, DmSyx6, SYX6/10, Syx, DmelCG7736, CG7736, AA437559, AI415714, AI845861, 2310039E05Rik, 2410005I16Rik, MGC78971, MGC132090, STX6, MGC151807, fb51b08, wu:fb51b08, zgc:110658, si:dkey-121a11.2, LOC734102, Syx6, Bmsyx6, Syntaxin-6, DKFZp459N181

Clonality: Polyclonal

Host: Rabbit

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350937

Additional Information

Alternative name: Syntaxin-6 (Stx6,Syntaxin 6)

Swiss-Prot: Q63635

Immunogen: A synthetic peptide as a part of rat, mouse Syntaxin-6 (Stx6, Syntaxin 6) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: FUNCTION: Involved in intracellular vesicle trafficking. SUBUNIT: Binds EEA1. Interacts with VPS45A and GOPC. Interacts with MARCH2 and MARCH3. Identified in a complex containing STX6, STX13, VAMP4 and VTI1A. SUBCELLULAR LOCATION: Golgi apparatus membrane; Single-pass type IV membrane protein. Also known as: Syntaxin-6, Stx6, Syntaxin 6.

Specificity: Appears to be specific for Syntaxin-6.

Synonyms: MGC93348, CT23545, Dm Syx6, DmSyx6, SYX6/10, Syx, DmelCG7736, CG7736, AA437559, AI415714, AI845861, 2310039E05Rik, 2410005I16Rik, MGC78971, MGC132090, STX6, MGC151807, fb51b08, wu:fb51b08, zgc:110658, si:dkey-121a11.2, LOC734102, Syx6, Bmsyx6, Syntaxin-6, DKFZp459N181

Application Details

Application Notes: IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Publications: Bock, Lin, Scheller: "A new syntaxin family member implicated in targeting of intracellular transport vesicles." in: The Journal of biological chemistry, Vol. 271, Issue 30, pp. 17961-5, 1996 (PubMed).

Simonsen, Gaullier, DArrigo et al.: "The Rab5 effector EEA1 interacts directly with syntaxin-6." in: The Journal of biological chemistry, Vol. 274, Issue 41, pp. 28857-60, 1999 (PubMed).

Misura, Bock, Gonzalez et al.: "Three-dimensional structure of the amino-terminal domain of syntaxin 6, a SNAP-25 C homolog." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 14, pp. 9184-9, 2002 (PubMed).

Nakamura, Fukuda, Kato et al.: "MARCH-II is a syntaxin-6-binding protein involved in endosomal trafficking." in: Molecular biology of the cell, Vol. 16, Issue 4, pp. 1696-710, 2005 (PubMed).

Carninci, Kasukawa, Katayama et al.: "The transcriptional landscape of the mammalian genome." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1559-63, 2005 (PubMed).

Fukuda, Nakamura, Hirose: "MARCH-III Is a novel component of endosomes with properties similar to those of MARCH-II." in: Journal of biochemistry, Vol. 139, Issue 1, pp. 137-45, 2006 (PubMed).