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Details for Product No. ABIN350942

Syntaxin 7 (STX7) antibody

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Antigen
Synonyms
Syn7, AI315064, AI317144, AW107239, Aval, Avl, CG5081, Dm Syx7, DmSyx7, Dmel\\CG5081, FCP-C, SYX7, Syx, avl, dSyn7, syx7, syx7/avl, syntaxin-7, F27G20.2, SYNTAXIN 24, SYP24, DDBDRAFT_0187598, DDBDRAFT ... show more
Reactivity
»Alternatives Human, Mouse (Murine), Rat (Rattus)
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN350942
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide as a part of human Syntaxin-7 (STX7, Syn7, Syntaxin 7) conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Specific for GABA(A) receptor subunit alpha-1.
Purity whole serum
Alternative Name Syntaxin-7 (STX7, Syn7,Syntaxin 7)
Background Function: May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes.
Subunit: Forms a SNARE complex with VTI1B, STX8 and VAMP8 which functions in the homotypic fusion of late endosomes. Interacts with VPS33A. Found in a complex with VAMP8 and VTI1B in the liver. Part of the SNARE core complex containing VAMP8, STX8 and VTI1B. Interacts with VPS11, VPS16 and VPS18.
Subcellular location: Early endosome membrane, Single-pass type IV membrane protein. Also known as: Syntaxin-7, STX7, Syn7.
UniProt P62813
Research Area Receptors
Application Notes A dilution of 1 : 300 to 1 : 5000 is recommended.
The optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
Expiry Date 12 months
Wang, Frelin, Pevsner: "Human syntaxin 7: a Pep12p/Vps6p homologue implicated in vesicle trafficking to lysosomes." in: Gene, Vol. 199, Issue 1-2, pp. 39-48, 1997 (PubMed).

Prekeris, Yang, Oorschot et al.: "Differential roles of syntaxin 7 and syntaxin 8 in endosomal trafficking." in: Molecular biology of the cell, Vol. 10, Issue 11, pp. 3891-908, 1999 (PubMed).

Nakamura, Yamamoto, Wada et al.: "Syntaxin 7 mediates endocytic trafficking to late endosomes." in: The Journal of biological chemistry, Vol. 275, Issue 9, pp. 6523-9, 2000 (PubMed).

Gevaert, Goethals, Martens et al.: "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides." in: Nature biotechnology, Vol. 21, Issue 5, pp. 566-9, 2003 (PubMed).

Mungall, Palmer, Sims et al.: "The DNA sequence and analysis of human chromosome 6." in: Nature, Vol. 425, Issue 6960, pp. 805-11, 2003 (PubMed).

Alternatives for antigen "Syntaxin 7 (STX7)", type "Antibodies"
Hosts (21), (3), (3), (1)
Reactivities (22), (9), (8)
Applications (26), (11), (8), (4), (3), (2), (2), (1), (1)
Epitopes (7), (3), (2), (1)
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