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Details for Product No. ABIN350945

Syntaxin-Binding Protein 1 (STXBP1) (Internal Region) antibody

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Antigen
Synonyms
ANC18HA, Munc18-1, NSEC1A, Sec1, Unc18-1, n-sec1, nSec1, rbSec1, rbSec1A, rbSec1B, fj43h10, stxbp1, wu:fj36d12, wu:fj43h10, zgc:114171, munc18-1, nsec1, rbsec1, unc18, MUNC18-1, NSEC1, P67, RBSEC1, UN ... show more
Epitope
»Alternatives Internal Region
Reactivity
»Alternatives Human, Rat (Rattus), Mouse (Murine), Chicken, Monkey
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN350945
Quantity 500 µg
Price
454.67 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from the internal part of human Syntaxin-binding protein 1 (STXB1, p67, N-Sec1, Unc-18A, Unc-18-1, rbSec1) conjugated to an immunogenic carrier protein was used as the immunogen. The immunogen is homologous with the corresponding sequence in rat, mouse, chicken and monkey.
Isotype IgG
Specificity Appears to be specific for Syntaxin-binding protein 1.
Purity IgG
Alternative Name Syntaxin-Binding Protein 1 (STXB1, Unc-18A)
Background Function: May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions. Also known as: STXB1, p67, N-Sec1, Unc-18A, Unc-18-1, rbSec1.
UniProt P61764
Application Notes IHC, WB. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Gengyo-Ando, Kitayama, Mukaida et al.: "A murine neural-specific homolog corrects cholinergic defects in Caenorhabditis elegans unc-18 mutants." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 16, Issue 21, pp. 6695-702, 1996 (PubMed).

Gotoh, Yokota, Kikuya et al.: "Genomic structure of MUNC18-1 protein, which is involved in docking and fusion of synaptic vesicles in brain." in: The Journal of biological chemistry, Vol. 273, Issue 34, pp. 21642-7, 1998 (PubMed).

Collins, Yu, Coba et al.: "Proteomic analysis of in vivo phosphorylated synaptic proteins." in: The Journal of biological chemistry, Vol. 280, Issue 7, pp. 5972-82, 2005 (PubMed).

Villén, Beausoleil, Gerber et al.: "Large-scale phosphorylation analysis of mouse liver." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 5, pp. 1488-93, 2007 (PubMed).

Ballif, Carey, Sunyaev et al.: "Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain." in: Journal of proteome research, Vol. 7, Issue 1, pp. 311-8, 2008 (PubMed).

Alternatives for antigen "Syntaxin-Binding Protein 1 (STXBP1)", type "Antibodies"
Hosts (69), (8), (7)
Reactivities (75), (58), (57), (17), (16), (12), (7), (5), (1), (1)
Applications (58), (41), (21), (20), (15), (8), (4), (2), (2), (1), (1)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (20), (9), (7), (5), (5), (3), (1), (1), (1), (1), (1), (1), (1)
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