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Details for Product No. ABIN350946

Syntaxin Binding Protein 6 (STXBP6) antibody

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Antigen
Synonyms MGC68796, zgc:86678, wu:fd20e06, amisyn, hspc156, MGC88977, STXBP6, LOC100226852
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 4 references available
Catalog no. ABIN350946
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide as a part of human Syntaxin-binding protein 5 (STXB5, Tomosyn-1, Llgl3) conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Appears to be specific for Syntaxin-binding protein 5.
Purity whole serum
Alternative Name Syntaxin-binding protein 5 (STXB5, Tomosyn-1, Llgl3)
Background Function: Inhibits translocation of GLUT4 from intracellular vesicles to the plasma membrane. Plays a regulatory role in calcium-dependent exocytosis and neurotransmitter release. Inhibits membrane fusion between transport vesicles and the plasma membrane. May modulate the assembly of trans-SNARE complexes between transport vesicles and the plasma membrane. Competes with STXBP1 for STX1 binding.
Subunit: Part of a complex that contains STXBP5, STX4A andSNAP23. Interacts with STX1A and STX4A via its v-SNARE homology domain. Part of a complex that contains STX1, STXBP5,SNAP25 and SYT1.
Subcellular location: Cytoplasm. Cell membrane, Peripheral membrane protein. Cytoplasmic vesicle membrane, Peripheral membrane protein. Cell junction, synapse. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Note: Cytoplasmic, and associated with vesicular membranes and the plasma membrane. Detected at synapses and on synaptic vesicles.
Tissue specificity: Isoform 1 is detected in heart, brain, lung, liver, skeletal muscle, kidney and testis. Isoform 2 is detected in brain and in testis. Isoform 3 is detected in testis. Also known as: Lethal(2) giant larvae protein homolog 3, STXB5, Tomosyn-1, Llgl3.
UniProt Q5T5C0
Application Notes IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Mungall, Palmer, Sims et al.: "The DNA sequence and analysis of human chromosome 6." in: Nature, Vol. 425, Issue 6960, pp. 805-11, 2003 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Zahedi, Lewandrowski, Wiesner et al.: "Phosphoproteome of resting human platelets." in: Journal of proteome research, Vol. 7, Issue 2, pp. 526-34, 2008 (PubMed).

Alternatives for antigen "Syntaxin Binding Protein 6 (STXBP6)", type "Antibodies"
Hosts (3), (1)
Reactivities (2), (1), (1), (1)
Applications (2), (1), (1), (1)
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