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Syntaxin-binding protein 5-like (Tomosyn-2, Stxbp5l, STB5L) (C-Term) antibody
Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
|3 references available|
|Quantity||100 µl (Variants)|
|Price||454.67 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 7 to 8 Business Days|
|Immunogen||A synthetic peptide as a part of mouse Syntaxin-binding protein 5-like, isoforms 1 to 5 (Tomosyn-2, Stxbp5l, Llgl4, STB5L) conjugated to an immunogenic carrier protein was used as the immunogen.|
|Description||FUNCTION: May play a role in vesicle trafficking and exocytosis. SUBCELLULAR LOCATION: Cytoplasm. Cell membrane; Peripheral membrane protein. Membrane; Peripheral membrane protein. Note: Cytoplasmic, and associated with vesicular membranes and the plasma membrane. TISSUE SPECIFICITY: Detected in hippocampus and cerebellum. Also known as: Tomosyn-2, Lethal(2) giant larvae protein homolog 4, Stxbp5l, Llgl4, LLGL4, STB5L.|
|Specificity||Appears to be specific for Stxbp5l.|
|Application Notes||IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.|
|Storage||Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.|
|Restrictions||For Research Use only|
|IF on 1 day- old mouse cortical cell culture using Rabbit antibody to mouse Syntaxin-binding protein 5-like, isoforms 1-5 (Tomosyn-2, Stxbp5l, Llgl4, STB5L): whole serum (ABIN350947) at 1: 2000 dilution. DAPI counter stained.|
Groffen, Jacobsen, Schut et al.: "Two distinct genes drive expression of seven tomosyn isoforms in the mammalian brain, sharing a conserved structure with a unique variable domain." in: Journal of neurochemistry, Vol. 92, Issue 3, pp. 554-68, 2005 (PubMed).
Carninci, Kasukawa, Katayama et al.: "The transcriptional landscape of the mammalian genome." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1559-63, 2005 (PubMed).
Munton, Tweedie-Cullen, Livingstone-Zatchej et al.: "Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 2, pp. 283-93, 2007 (PubMed).
|Hosts||Rabbit (2), Goat (1)|
|Applications||Immunohistochemistry (IHC) (3), Western Blotting (WB) (3)|