Syntaxin-binding protein 5-like (Tomosyn-2, Stxbp5l, STB5L) (C-Term) antibody

Antigen: Syntaxin-binding protein 5-like (Tomosyn-2, Stxbp5l, STB5L)

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350947

Additional Information

UniProt: Q5DQR4

Immunogen: A synthetic peptide as a part of mouse Syntaxin-binding protein 5-like, isoforms 1 to 5 (Tomosyn-2, Stxbp5l, Llgl4, STB5L) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: FUNCTION: May play a role in vesicle trafficking and exocytosis. SUBCELLULAR LOCATION: Cytoplasm. Cell membrane; Peripheral membrane protein. Membrane; Peripheral membrane protein. Note: Cytoplasmic, and associated with vesicular membranes and the plasma membrane. TISSUE SPECIFICITY: Detected in hippocampus and cerebellum. Also known as: Tomosyn-2, Lethal(2) giant larvae protein homolog 4, Stxbp5l, Llgl4, LLGL4, STB5L.

Specificity: Appears to be specific for Stxbp5l.

Application Details

Application Notes: IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Images

IF on 1 day- old mouse cortical cell culture using Rabbit antibody to mouse Syntaxin-binding protein 5-like, isoforms 1-5 (Tomosyn-2, Stxbp5l, Llgl4, STB5L): whole serum (ABIN350947) at 1: 2000 dilution. DAPI counter stained.

Publications

Groffen, Jacobsen, Schut et al.: "Two distinct genes drive expression of seven tomosyn isoforms in the mammalian brain, sharing a conserved structure with a unique variable domain." in: Journal of neurochemistry, Vol. 92, Issue 3, pp. 554-68, 2005 (PubMed).

Carninci, Kasukawa, Katayama et al.: "The transcriptional landscape of the mammalian genome." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1559-63, 2005 (PubMed).

Munton, Tweedie-Cullen, Livingstone-Zatchej et al.: "Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 2, pp. 283-93, 2007 (PubMed).