Taste Receptor, Type 1, Member 1 (TAS1R1) (internal part) antibody

Antigen: Taste Receptor, Type 1, Member 1 (TAS1R1)

Synonyms: Gpr70, TR1, T1R1, GPR70, gm148, T1r1, TAS1R1

Epitope: internal part

Clonality: Polyclonal

Host: Rabbit

Reactivity: Zebrafish (Danio rerio)

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350950

Additional Information

Alternative name: taste receptor, type 1, member 1 (Tas1r1, Gpr70, T1r1, Tr1, TS1R1) (internal part)

Swiss-Prot: Q2MHL2

Immunogen: A synthetic peptide from the internal part of zebrafish taste receptor, type 1, member 1 (Tas1r1, Gpr70, T1r1, Tr1, TS1R1) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: FUNCTION: Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate) and also to most of the 20 standard L-amino acids, but not to their D-enantiomers or other compounds. Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses. SUBUNIT: Forms heterodimers with TAS1R3. SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed strongly only in fungiform papillae.<||a href="http://www.enzim.hu/hmmtop1.1/server/submit.html" ><||/a> Also known as: Taste receptor type 1 member 1, Tas1r1, Gpr70, T1r1, Tr1, TS1R1.

Specificity: Appears to be specific for TAS1R1.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Publications: Ishimaru, Okada, Naito et al.: "Two families of candidate taste receptors in fishes." in: Mechanisms of development, Vol. 122, Issue 12, pp. 1310-21, 2005 (PubMed).