Trace Amine Associated Receptor 1 (TAAR1) (Cytoplasmic Domain) antibody

Details for Product No. ABIN350953
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Antigen
Synonyms Tar1, Trar1, taR-1, RP11-295F4.9, TA1, TAR1, TRAR1
Epitope
Cytoplasmic Domain
(6), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Rat (Rattus), Mouse (Murine), Xenopus laevis
(28), (10), (5), (5), (2)
Host
Goat
(30), (1), (1)
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(22), (20), (8), (3), (1)
Pubmed 5 references available
Catalog no. ABIN350953
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen A synthetic peptide from the 3d cytoplasmic domain of rat TAS1R1 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in mouse and shares 95% identity with human sequence.
Specificity Specific for Fibrillarin.
Purification whole serum
Alternative Name TAR1
Background Function: Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate) and also to most of the 20 standard L-amino acids, but not to their D-enantiomers or other compounds. Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.
Subunit: Forms heterodimers with TAS1R3.
Subcellular location: Cell membrane, Multi-pass membrane protein.
Tissue specificity: Expressed strongly only in fungiform papillae. Also known as: Taste receptor type 1 member 1, Tas1r1, Gpr70, T1r1, Tr1, TS1R1.
UniProt Q6P623
Research Area Chromatin and Nuclear Signaling, Chromatin Binding Proteins
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Liquid
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term.
Expiry Date 12 months
General Li, Inoue, Reed et al.: "High-resolution genetic mapping of the saccharin preference locus (Sac) and the putative sweet taste receptor (T1R1) gene (Gpr70) to mouse distal Chromosome 4." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 12, Issue 1, pp. 13-6, 2001 (PubMed).

Montmayeur, Liberles, Matsunami et al.: "A candidate taste receptor gene near a sweet taste locus." in: Nature neuroscience, Vol. 4, Issue 5, pp. 492-8, 2001 (PubMed).

Nelson, Hoon, Chandrashekar et al.: "Mammalian sweet taste receptors." in: Cell, Vol. 106, Issue 3, pp. 381-90, 2001 (PubMed).

Nelson, Chandrashekar, Hoon et al.: "An amino-acid taste receptor." in: Nature, Vol. 416, Issue 6877, pp. 199-202, 2002 (PubMed).

Ariyasu, Matsumoto, Kyono et al.: "Taste receptor T1R3 is an essential molecule for the cellular recognition of the disaccharide trehalose." in: In vitro cellular & developmental biology. Animal, Vol. 39, Issue 1-2, pp. 80-8, 2003 (PubMed).

Hosts (30), (1), (1)
Reactivities (28), (10), (5), (5), (2)
Applications (22), (20), (8), (3), (1)
Epitopes (6), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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