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Details for Product No. ABIN350954

Taste Receptor, Type 1, Member 1 (Tas1r1, TS1R1) (4th Cytoplasmic Domain) antibody

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Antigen
Epitope
»Alternatives 4th Cytoplasmic Domain
Reactivity
»Alternatives Mouse (Murine), Rat (Rattus), Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN350954
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from the 4th cytoplasmic domain of mouse taste receptor, type 1, member 1 (Tas1r1, Gpr70, T1r1, TS1R1) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in rat and shares 92% identity with human's.
Specificity Appears to be specific for TAS1R1.
Purity whole serum
Background Function: Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate) and also to most of the 20 standard L-amino acids, but not to their D-enantiomers or other compounds. Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.
Subunit: Forms heterodimers with TAS1R3.
Subcellular location: Cell membrane, Multi-pass membrane protein.
Tissue specificity: Expressed strongly only in fungiform papillae. Also known as: Taste receptor type 1 member 1, Tas1r1, Gpr70, T1r1, Tr1, TS1R1.
UniProt Q99PG6
Application Notes IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Li, Inoue, Reed et al.: "High-resolution genetic mapping of the saccharin preference locus (Sac) and the putative sweet taste receptor (T1R1) gene (Gpr70) to mouse distal Chromosome 4." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 12, Issue 1, pp. 13-6, 2001 (PubMed).

Montmayeur, Liberles, Matsunami et al.: "A candidate taste receptor gene near a sweet taste locus." in: Nature neuroscience, Vol. 4, Issue 5, pp. 492-8, 2001 (PubMed).

Nelson, Hoon, Chandrashekar et al.: "Mammalian sweet taste receptors." in: Cell, Vol. 106, Issue 3, pp. 381-90, 2001 (PubMed).

Nelson, Chandrashekar, Hoon et al.: "An amino-acid taste receptor." in: Nature, Vol. 416, Issue 6877, pp. 199-202, 2002 (PubMed).

Ariyasu, Matsumoto, Kyono et al.: "Taste receptor T1R3 is an essential molecule for the cellular recognition of the disaccharide trehalose." in: In vitro cellular & developmental biology. Animal, Vol. 39, Issue 1-2, pp. 80-8, 2003 (PubMed).

Alternatives for antigen "Taste Receptor, Type 1, Member 1 (Tas1r1, TS1R1)", type "Antibodies"
Hosts (2)
Reactivities (2), (1), (1)
Applications (2), (2)
Epitopes (1), (1)
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