taste receptor, type 1, member 2 (TAS1R2, TS1R2) (C-Term) antibody

Antigen: taste receptor, type 1, member 2 (TAS1R2, TS1R2)

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350955

Additional Information

UniProt: Q8TE23

Immunogen: A synthetic peptide from human taste receptor, type 1, member 2 (TAS1R2, TR2, T1R2, GPR71, TS1R2) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: FUNCTION: Putative taste receptor. TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. SUBUNIT: Forms heterodimers with TAS1R3. SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.<||a href="http://www.enzim.hu/hmmtop1.1/server/submit.html" /> Also known as: Taste receptor type 1 member 2 (precursor), sweet taste receptor T1R2, G-protein coupled receptor 71, TAS1R2, TR2, T1R2, GPR71, TS1R2.

Specificity: Appears to be specific for TAS1R2.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Li, Staszewski, Xu et al.: "Human receptors for sweet and umami taste." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 7, pp. 4692-6, 2002 (PubMed).

Gregory, Barlow, McLay et al.: "The DNA sequence and biological annotation of human chromosome 1." in: Nature, Vol. 441, Issue 7091, pp. 315-21, 2006 (PubMed).