Taste Receptor, Type 1, Member 2 (TAS1R2) (1t extracellular domain TAS1R2 TR2 T1R2 GPR71 TS1R2) antibody

Antigen: Taste Receptor, Type 1, Member 2 (TAS1R2)

Synonyms: TR2, T1R2, GPR71, T1r2, Gpr71, Tas1r2, Tr2, Aldh4a1, TAS1R2

Epitope: 1t extracellular domain TAS1R2 TR2 T1R2 GPR71 TS1R2

Clonality: Polyclonal

Host: Rabbit

Reactivity: Rat (Rattus)

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350956

Additional Information

Alternative name: taste receptor, type 1, member 2 (TAS1R2, TR2, T1R2, GPR71, TS1R2) (1t extracellular domain)

Swiss-Prot: Q9Z0R7

Immunogen: A synthetic peptide from the 1t extracellular domain of rat taste receptor, type 1, member 2 (TAS1R2, TR2, T1R2, GPR71, TS1R2) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen shares 80% identity with the mouse sequence.

Format: Lyophilized

Description: FUNCTION: Putative taste receptor. TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. SUBUNIT: Forms heterodimers with TAS1R3. SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.<||a href="http://www.enzim.hu/hmmtop1.1/server/submit.html" ><||/a> Also known as: Taste receptor type 1 member 2, sweet taste receptor T1R2, G-protein coupled receptor 71, TAS1R2, TR2, T1R2, GPR71, TS1R2.

Specificity: Appears to be specific for TAS1R2.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Publications: Hoon, Adler, Lindemeier et al.: "Putative mammalian taste receptors: a class of taste-specific GPCRs with distinct topographic selectivity." in: Cell, Vol. 96, Issue 4, pp. 541-51, 1999 (PubMed).