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Taste Receptor, Type 1, Member 2 (TAS1R2) antibody

Details for Product No. ABIN350957, Supplier: Log in to see
Antigen
  • Aldh4a1
  • Gpr71
  • GPR71
  • T1R2
  • T1r2
  • TR2
  • Tr2
Reactivity
Mouse (Murine)
58
17
16
1
Host
Rabbit
49
16
Clonality
Polyclonal
Conjugate
Un-conjugated
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
46
31
11
8
5
1
1
1
1
Supplier
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Immunogen A synthetic peptide from mouse TAS1R2 conjugated to an immunogenic carrier protein was used as the antigen.
Specificity Specific for TAS1R2.
Purification Whole serum
Alternative Name TAS1R2 (TAS1R2 Antibody Abstract)
Background Function: Putative taste receptor. TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners.
Subunit: Forms heterodimers with TAS1R3.
Subcellular location: Cell membrane, Multi-pass membrane protein.
Tissue specificity: Expressed mainly in circumvallate and foliate taste papillae.Also known as: Taste receptor type 1 member 2, sweet taste receptor T1R2, G-protein coupled receptor 71, Tas1r2, Gpr71, T1r2, Tr2, TS1R2.
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Ariyasu, Matsumoto, Kyono, Hanaya, Arai, Ikeda, Kurimoto: "Taste receptor T1R3 is an essential molecule for the cellular recognition of the disaccharide trehalose." in: In vitro cellular & developmental biology. Animal, Vol. 39, Issue 1-2, pp. 80-8, 2003 (PubMed).

Montmayeur, Liberles, Matsunami, Buck: "A candidate taste receptor gene near a sweet taste locus." in: Nature neuroscience, Vol. 4, Issue 5, pp. 492-8, 2001 (PubMed).

Nelson, Hoon, Chandrashekar, Zhang, Ryba, Zuker: "Mammalian sweet taste receptors." in: Cell, Vol. 106, Issue 3, pp. 381-90, 2001 (PubMed).